Non-Enzymatic Glucose Sensing Based on Incorporation of Carbon Nanotube into Zn-Co-S Ball-in-Ball Hollow Sphere

Abstract

Zn-Co-S ball-in-ball hollow sphere (BHS) was successfully prepared by solvothermal sulfurization method. An efficient strategy to synthesize Zn-Co-S BHS consisted of multilevel structures by controlling the ionic exchange reaction was applied to obtain great performance electrode material. Carbon nanotubes (CNTs) as a conductive agent were uniformly introduced with Zn-Co-S BHS to form Zn-Co-S BHS/CNTs and expedited the considerable electrocatalytic behavior toward glucose electro-oxidation in alkaline medium. In this study, characterization with scanning electron microscopy (SEM), transmission electron microscopy (TEM), X-ray photoelectron spectroscopy (XPS), and X-ray diffraction (XRD) was used for investigating the morphological and physical/chemical properties and further evaluating the feasibility of Zn-Co-S BHS/CNTs in non-enzymatic glucose sensing. Electrochemical methods (cyclic voltammetry (CV) and chronoamperometry (CA)) were performed to investigate the glucose sensing performance of Zn-Co-S BHS/CNTs. The synergistic effect of Faradaic redox couple species of Zn-Co-S BHS and unique conductive network of CNTs exhibited excellent electrochemical catalytic ability towards the glucose electro-oxidation, which revealed linear range from 5 to 100 μM with high sensitivity of 2734.4 μA mM−1 cm−2, excellent detection limit of 2.98 μM, and great selectivity in the presence of dopamine, uric acid, ascorbic acid, and fructose. Thus, Zn-Co-S BHS/CNTs would be expected to be a promising material for non-enzymatic glucose sensing.

Metal-organic framework derived porous hollow ZnCo2S4 improving electrocatalytic oxidation of glucose

“…As a result, ZnCo 2 S 4 electrode materials exhibit high sensitivity, wide detection lines, and low detection limits, which also make them excellent sensing materials for the electrocatalytic oxidation of glucose. In addition, we compared ZnCo 2 S 4 with other glucose electrocatalytic oxidation materials, showing the excellent electrochemical properties of the ZnCo 2 S 4 material (table 1) [8,[37][38][39][40][41][42][43] To study the specificity of the sensor for glucose, we selected some common organic and inorganic substances that may cause interference, including NaCl, urea (UA), ascorbic acid (AA), hydrogen peroxide (H 2 O 2 ), and SO 4 2− , the concentration of each interfering sample is 1M, and the time interval is the 50s. The results are shown in figure 6(d), even if the concentration of the interfering sample is dozens of times higher than that of glucose, ZnCo 2 S 4 nanomaterials still have no obvious response to these interfering substances.…”

Engineering of a self-supported carbon electrode with 2D ultrathin heterostructures of NiCo LDH/NiCoS via a MOF-template for sensitive detection of glucose and H2O2

“…A Zn–Co–S ball-in-ball hollow sphere (BHS) was obtained via ion exchange and a sulfidation method for highly selective glucose detection with a sensitivity of up to 2734.4 μA mM −1 cm −2 and a wide detection range of 5–100 μM. 19 Ni 2.5 Mo 6 S 6.7 was grown on poly(3,4-ethylenedioxythiophene)–reduced graphene oxide (PEDOT–rGO) hybrid membranes via electrodeposition to obtain Ni 2.5 Mo 6 S 6.7 /PEDOT–rGO with high sensitivities toward glucose (666.67 and 266.10 μA mM −1 cm −2 ) and H 2 O 2 (1273.52 μA mM −1 cm −2 ). 20 However, the multiple electron transfer reactions in the detection process make TMS less reversible, resulting in unsatisfactory stability.…”

Construction of a Label-Free Electrochemical Immunosensor Based on Zn-Co-S/Graphene Nanocomposites for Carbohydrate Antigen 19-9 Detection

“…Recent investigations have shown that transition metal sulfide nanomaterials, such as MoS 2 [7], CoS 2 [8], CuS [9], and NiCo 2 S 4 [10], were suitable for preparing electrochemical immunosensors that displayed the superior sensing performance. Such an effect was acknowledged to be partly caused by the lower electronegativity of S, which exhibited remarkable electrochemical performance [11,12]. Considering the attractive properties of graphene, greatly enhanced electrocatalytic sensing can be achieved by integrating graphene with transition metal sulfide nanomaterials.…”