Non-enzymatic glucose sensor based on three dimensional nickel oxide for enhanced sensitivity

Guo, Chunyan; Wang, Yinmei; Zhang, Yongqing; Xu, Cailing

doi:10.1039/c3ay00067b

Cited by 120 publications

(73 citation statements)

References 26 publications

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“…Second, negative charge repulsion between the surface of NiO in 0.1 M NaOH electrolyte and interfering species also favored the selective oxidation of Glu. [ 37 ] The results in this study suggested that the interfering effect caused by the electroactive species was quite negligible, validating the highly selective detection of Glu by the NCD sphere electrode.…”

Section: Selectivity Of the Ncd Sphere Electrodesupporting

confidence: 70%

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

Akhtar

El‐Safty

Abdelsalam

et al. 2015

Adv Healthcare Materials

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Selective and sensitive glucose sensors with fast response for screening diabetic blood level are demanded. In this paper, the one-pot nanoarchitecture of dendritic NiO@carbon-nitrogen (C-N) dots (designated as NCD) sphere-wrapping Ni foam electrodes are reported as an effective and sensitive glucose sensor in blood samples. In this construction design, the NCD sphere electrode with excessive surface defects, large fractions of catalytic active sites, high surface area, and mobility of electron transfer through the actively surface NCD sphere can massively enhance the electrocatalytic activity for nonenzymatic glucose detection in diabetic blood. This portable sensor enables highly sensitive recognition of glucose detection (≈0.01 × 10 m) over a wider linear range (≈0.005-12 × 10 m) with rapid response time of a few seconds. The key result is that the engineered NCD sphere electrodes function as simple, easy-to-use electrochemical sensing assays of glucose levels in diabetic blood patients with a wide range of precision or linearity, recyclability, and excellent selectivity, even in the presence of potentially interfering organic (ascorbic acid, uric acid, dopamine, lactose, maltose, and sucrose) and inorganic (NaCl, Na SO , KCl, and K SO ) species. The results demonstrate the potential for the electrochemical sensors to be used in preventing serious health problems associated with diabetes mismanagement.

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Section: Selectivity Of the Ncd Sphere Electrodesupporting

confidence: 70%

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

Akhtar

El‐Safty

Abdelsalam

et al. 2015

Adv Healthcare Materials

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“…It is therefore expected the direct use of Ni foil is more convenient and applicable to he glucose sensor chip, but the sensitivity of this sensor only achieved 670 µA/mM-cm 2 [18]. Ni foam has been drawn attentions due to its advantages such as high conductivity, three dimensional network structure and much higher loading amount of active materials per unit electrode area [19][20][21]. Nanostructure materials possess large surface-to-volume ratio and high active sites, thus favoring a greater and faster reaction between the glucose solution and the electrode.…”

Section: Introductionmentioning

confidence: 99%

Preparation of Ni(OH)₂ nanosheets on Ni foam via a direct precipitation method for a highly sensitive non-enzymatic glucose sensor

Zhao

You

et al. 2015

RSC Adv.

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Ni(OH)2 nanosheets on Ni foam was prepared by the direct precipitation method. The morphology and phase composition of the as-prepared Ni(OH)2 nanosheets/Ni electrode were characterized by scanning electron microscopy and X-ray diffraction, respectively. The electrode's electrochemical behavior was investigated by cyclic voltammetry and the constant potential amperometry technique. The best performance of the glucose sensor can be obtained at 0.51 V in 0.2 M sodium hydroxide solution. The as-prepared Ni(OH)2 nanosheets/Ni electrode shows high sensitivity with 1130 μAmM-1cm -2 at the glucose concentration range of 2 μM to 40 μM and 1097 μAmM -1 cm -2 at the range of 0.1 mM to 2.5 mM. The response time of this electrode is less than 2 seconds, and its detection limit is 1 μM.

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“…Different metal oxide nanostructure based enzyme free glucose sensors have been proposed and studied during last few years. However, most commodiously used metal oxides include NiO Mu et al 2011;Guo et al 2013), MnO 2 (Chen et al 2008), Co 3 O 4 (Wang et al 2012), and CuO (Wang et al 2012). Nevertheless, there is still plenty of room to explore new and novel morphologies of metal oxide nanostructures obtained via reliable and reproducible synthetic strategies for the fabrication of enzyme free glucose sensors.…”

Section: Introductionmentioning

confidence: 99%

Practice of diclofenac sodium for the hydrothermal growth of NiO nanostructures and their application for enzyme free glucose biosensor

et al. 2015

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Non-enzymatic glucose sensor based on three dimensional nickel oxide for enhanced sensitivity

Cited by 120 publications

References 26 publications

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

Preparation of Ni(OH)₂ nanosheets on Ni foam via a direct precipitation method for a highly sensitive non-enzymatic glucose sensor

Practice of diclofenac sodium for the hydrothermal growth of NiO nanostructures and their application for enzyme free glucose biosensor

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Non-enzymatic glucose sensor based on three dimensional nickel oxide for enhanced sensitivity

Cited by 120 publications

References 26 publications

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

One‐Pot Fabrication of Dendritic NiO@carbon–nitrogen Dot Electrodes for Screening Blood Glucose Level in Diabetes

Preparation of Ni(OH)2 nanosheets on Ni foam via a direct precipitation method for a highly sensitive non-enzymatic glucose sensor

Practice of diclofenac sodium for the hydrothermal growth of NiO nanostructures and their application for enzyme free glucose biosensor

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Preparation of Ni(OH)₂ nanosheets on Ni foam via a direct precipitation method for a highly sensitive non-enzymatic glucose sensor