To evaluate the nanosecond pulsed discharge plasma-assisted evaporation and ignition attributes of hydrocarbon fuel droplets, numerical models are established. The influences of nonequilibrium plasma on the characteristics of n-decane droplet evaporation and ignition are numerically studied through a loosely coupled method employing a one-dimensional (1D) fully transient model of droplet evaporation and ignition and a model of nanosecond pulse plasma discharge. The results show that the reaction rate of the initial phase of n-decane droplet ignition is increased by nonequilibrium plasma. In addition, both the evaporation and ignition of the droplet are accelerated. Increasing the reduced electric field of the discharge leads to decreases in the droplet ignition delay time, survival time, and shortening amplitude. The evaporative cooling effect, which occurs at the initial phase of droplet ignition and typically decreases the local temperature surrounding a droplet surface, is weakened by the plasma. As the reduced electric field increases, the time to generate a high-temperature zone (>1800 K) decreases, while its duration increases. The initial phase of n-decane droplet ignition, in which the flame temperature increases while the flame radius decreases, is strongly affected by the plasma during the initial ignition phase. However, the plasma has little impact on the peak flame temperature and the flame radius during the stable combustion phase of the droplet. According to reaction kinetics analysis, the plasma directly interferes with the elementary reactions R330 (nC10H22 + O = 3-C10H21 + OH) and R331 (nC10H22 + O = 2-C10H21 + OH) of n-decane/air combustion. Moreover, the dissociation and oxidation processes of intermediate products are accelerated. Then, the important reaction rates, which determine the ignition delay time, increase indirectly. Thus, the overall ignition delay time of the n-decane droplet is shortened.