Non-extractable Procyanidins and Lignin are Important Factors in the Bile Acid Binding and Radical Scavenging Properties of Cell Wall Material in some Fruits

Hamauzu, Yasunori; Mizuno, Yukari

doi:10.1007/s11130-010-0207-z

Cited by 55 publications

(37 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Probably, the combination between non‐extractable phenolic compounds and undegradable polysaccharides may be an important factor for the mycotoxin adsorption by selected agricultural by‐products. It has been reported that fibres with associated tannins show broader functions than fibres without them . High contents of cellulose, lignin, and tannins in fruits have been found essential for bile acids binding activity, and removal of tannins from fibre resulted in a sharp decrease of this activity .…”

Section: Discussionmentioning

confidence: 99%

Comparative efficacy of agricultural by‐products in sequestering mycotoxins

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Comparative efficacy of agricultural by‐products in sequestering mycotoxins

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Nevertheless, the results constitute evidence of an appreciable presence of NEPP in plant foods and of their contribution to total polyphenol intake. (31) Quince 48 (32) Banana 980 (SD 45)* (27) Apple pomace 18 -23 (33) Cranberry pomace 1685 (34) Cocoa powder 602 (SD 13) (35) Carob pod 180 (36) Hydrolysable phenolics Onion 410 (SD 20)* (37) Black olive 14 -40 (38) Apple 78 (SD 6) (29) Medlar 0·5 -1·0 (39) Mandarin 39 -107 (40) Acerola 390 (SD 10)* (41) Cashew apple 1210 (SD 70)* † (41) Black currant pomace…”

Section: Occurrence Of Non-extractable Polyphenols In Dietsmentioning

confidence: 99%

Non-extractable polyphenols, a major dietary antioxidant: occurrence, metabolic fate and health effects

2013

View full text Add to dashboard Cite

Current research on dietary antioxidants misses the so-called non-extractable polyphenols (NEPP), which are not significantly released from the food matrix either by mastication, acid pH in the stomach or action of digestive enzymes, reaching the colon nearly intact. NEPP, not detected by the usual analytical procedures, are made up of macromolecules and single phenolic compounds associated with macromolecules. Therefore, NEPP are not included in food and dietary intake data nor in bioavailability, intervention or observational studies. The present paper aims to provide an overview of dietary NEPP -nature, occurrence in diet, metabolic fate and possible health effects. NEPP are a relevant fraction of dietary polyphenols exerting their main biological action in the colon, where they are extensively fermented by the action of microbiota, giving place to absorbable metabolites. NEPP exhibit different potential health-related properties, in particular in relation to gastrointestinal health, such as increases in antioxidant and antiproliferative capacities, reduction of intestinal tumorigenesis and modification of gene expression, as observed in different animal models. Further research into NEPP may provide a better understanding of the health effects of dietary antioxidants.

show abstract

“…Assay for total phenol content was based on reduction of the molybdenum-tungstate complex in F-C Reagent by phenols (Herald, Gadgil, & Tilley, 2012). The procedure was adapted to 96-well microplate platform (250 µL assay volume per well) with absorbance acquired at λ 765 nm using a microplate reader (Multiskan GO, Thermo Scientific, Australia) at 25°C.…”

Section: Total Polyphenol Content (Tpc)mentioning

confidence: 99%

“…However these residual solids have been found to contain a large amount of polyphenols including polymeric proanthocyanidins (PC). Some of the PCs are strongly bound to cell wall components (Hamauzu & Mizuno, 2011), and Perez-Jimenez, Elena Diaz-Rubio, and Saura-Calixto (2013) indicated that BPPs contribute 60-90% to the total polyphenol content in most fruits. These studies have emphasised the importance of including the bound (non-extractable) polyphenols in plant polyphenol analysis.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant activities and inhibitory effects of free and bound polyphenols from date (Phoenix dactylifera L.) seeds on starch digestive enzymes

Sirisena

Ajlouni

2016

IJFS

View full text Add to dashboard Cite

Date (Phoenix dactylifera L.) seeds have gained interest as a valuable by-product of the date fruit industry and have been identified as a rich source of functional and bioactive ingredients. In this study, date seeds from five varieties (Medjool, Deglet Nour, Barhee, Bou Sthammi and Dayrie) cultivated in Australia were analysed for their total phenolic and flavonoid contents, ferric reducing antioxidant power (FRAP), Trolox equivalent antioxidant capacity (TEAC), and in-vitro inhibition against α-amylase and α-glucosidase. The date seed powders (DSP) were extracted with acetone-methanol-water (2:2:1, v:v:v) to obtain free polyphenols. The bound polyphenols were extracted from the residual solids with butanolHCl (97.5:2.5; v/v) treatment at 100°C. The greatest quantities of total phenols (4166±227 mg Gallic Acid Equivalents 100g −1 DSP), total flavonoids (52.1±9.6 mg Quercetin Equivalents 100g −1 DSP), FRAP (1589±47 µmol Iron (II) Equivalents g −1 DSP) and TEAC (45.2±1.4 µmol Trolox Equivalents g −1 DSP) were detected in seeds from Deglet Nour variety. Both free and bound polyphenol fractions showed significant (p<0.05) inhibition against rat intestinal α-glucosidase with little or no inhibition against pancreatic α-amylase. Bound polyphenols showed stronger α-glucosidase inhibition compared with free polyphenols. The IC50 for α-glucosidase were reported as mg GAE mL −1 ranged from 0.39±0.02 (Deglet Nour ) to 0.68±0.02 (Medjool ) for bound polyphenols, and from 0.907±0.08 (Medjool ) to 1.75±0.15 (Barhee-khalal ) for free polyphenols. Bound polyphenol fraction, with strong α-glucosidase inhibition and weak α-amylase inhibition, was suggested as a significant source of functional food ingredients with anti-hyperglycaemic properties.

show abstract

Non-extractable Procyanidins and Lignin are Important Factors in the Bile Acid Binding and Radical Scavenging Properties of Cell Wall Material in some Fruits

Cited by 55 publications

References 26 publications

Comparative efficacy of agricultural by‐products in sequestering mycotoxins

Comparative efficacy of agricultural by‐products in sequestering mycotoxins

Non-extractable polyphenols, a major dietary antioxidant: occurrence, metabolic fate and health effects

Antioxidant activities and inhibitory effects of free and bound polyphenols from date (Phoenix dactylifera L.) seeds on starch digestive enzymes

Contact Info

Product

Resources

About