Non-Gastroenteritis Findings In Rotavirus Infections

Seçilmiş, Yılmaz; Esen, Feyza; Doğan, Murat; Öztürk, Mehmet

doi:10.16919/bozoktip.482030

Cited by 1 publication

(1 citation statement)

References 12 publications

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“…The majority of seasonal acute gastroenteritis in children is due to virus infections (primarily rotavirus). 25 Celiac autoantibodies' binding to rotavirus viral capsid protein-7 (VP-7) in celiac patients' serum also supports this relationship. 26 In terms of immunology, the rotavirus viral capsid antigen may serve as the necessary trigger for CD development.…”

Section: Discussionmentioning

confidence: 89%

Does Having Rotavirus Infection in Early Childhood Increase the Risk of Celiac Disease?

Başaran

Dogan

Bal

et al. 2021

Journal of Pediatric Infectious Diseases

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Objective With the increasing prevalence of celiac disease (CD) in the population, possible risk factors are under investigation. Environmental and genetic factors that trigger the immune response have been analyzed for many years. This study investigates the presence of CD in children with rotavirus infection. Rotavirus infection is thought to be a risk factor for CD. Methods Included in the study were 105 of 160 pediatric patients hospitalized due to symptomatic rotavirus infection between 2012 and 2018. These children were screened for CD 45.6 ± 18.2 (14–90) months following the rotavirus infection diagnosed with CD as per ESPGHAN guidelines. Results A total of 105 pediatric patients who had rotavirus gastroenteritis were included in the study. The age of the children with rotavirus infection was 3.98 ± 1 (2–6) months. In terms of CD, it was 45.6 ± 18.2 months. Around 14 to 90 months later, patients were called for control. CD developed in four (3.8%) of the children with rotavirus, whereas none of the children in the control group developed CD. Conclusion Rotavirus infection may be a risk factor for CD through immune mechanisms. There are genetic and various environmental factors for the development of CD. Although the CD's occurrence on children who had rotavirus gastroenteritis in our study also supported this situation, there was no statistically significant difference.

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Section: Discussionmentioning

confidence: 89%