Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation

Arias, Hugo R.; Micheli, Laura; Rudin, Deborah; Bento, Ophelie; Borsdorf, Saskia; Ciampi, Clara; Marin, Philippe; Ponimaskin, Evgeni; Manetti, Dina; Romanelli, Maria Novella; Ghelardini, Carla; Liechti, Matthias E.; Di Cesare Mannelli, Lorenzo

doi:10.1016/j.biopha.2024.116867

Biomedicine & Pharmacotherapy

2024

DOI: 10.1016/j.biopha.2024.116867

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Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation

Hugo R. Arias,

Laura Micheli,

Deborah Rudin

et al.

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The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission

Arias,

Rudin,

Luethi

et al. 2025

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission

Arias,

Rudin,

Luethi

et al. 2025

Progress in Neuro-Psychopharmacology and Biological Psychiatry

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Non-hallucinogenic compounds derived from iboga alkaloids alleviate neuropathic and visceral pain in mice through a mechanism involving 5-HT2A receptor activation

Cited by 1 publication

References 53 publications

The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission

The psychoplastogens ibogaminalog and ibogainalog induce antidepressant-like activity in naïve and depressed mice by mechanisms involving 5-HT2A receptor activation and serotonergic transmission

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