Abstract. This is a continuation of the work initiated in [18] on so-called driven cofactor systems, which are partially decoupling second-order differential equations of a special kind. The main purpose in [18] was to obtain an intrinsic, geometrical characterization of such systems, and to explain the basic underlying concepts in a brief note. In the present paper we address the more intricate part of the theory. It involves in the first place understanding all details of an algorithmic construction of quadratic integrals and their involutivity. It secondly requires explaining the subtle way in which suitably constructed canonical transformations reduce the HamiltonJacobi problem of the (a priori time-dependent) driven part of the system into that of an equivalent autonomous system of Stäckel type.