Non‐healing ulcer on penis

Necrobiosis lipoidica of the glans penis: a case report and literature review

“…Necrobiosis lipoidica affecting areas other than typical predilection sites (pretibial skin) has been shown to be less strongly associated with diabetes [ 1 ] ; nonetheless, four of the eight patients with NL of the penis, including our case, had a history of diabetes. Although it has been reported that the clinical course of NL may be independent of strict diabetes control [ 2 ] , one of the reported individuals showed improvement in his skin condition once his diabetes was well controlled [ 1 ] .…”

“…Necrobiosis lipoidica is a distinctive granulomatous dermatosis histologically characterized by necrosis of dermal collagen surrounded by palisading histiocytes [ 1 ] . Although lesions are typically located in the pretibial region, other areas of the body may also be affected [ 2 ] . With only seven cases reported to date, the penis is a rare site of involvement [1][2][3][4][5][6][7] .…”

“…Although lesions are typically located in the pretibial region, other areas of the body may also be affected [ 2 ] . With only seven cases reported to date, the penis is a rare site of involvement [1][2][3][4][5][6][7] . Based on a review of the literature, NL of the penis characteristically occurs on the glans, with one or more recurrent ulcers on an erythematous base that heal with depressed scars.…”