Non-Hodgkin Lymphoma Epidemiology in Children From 2 Socioeconomic Regions in Mexico: 20-Year Registry (1996-2015)

Abstract

Purpose: We analyzed the epidemiologic characteristics of different types of non-Hodgkin Lymphoma (NHL), excluding Burkitt Lymphoma, in 2 Mexican regions with different socioeconomic status. Materials and Methods: In this surveillance study, we analyzed the incidence rates (cases per million children/year) of different types of NHL according to the ICCC3, registered in 1996-2015, from 2 different socioeconomic regions in Mexico: central and southern, with higher and lower status, respectively. Results: The principal NHL subgroups were precursor (IIb1), mature B cell (IIb2), mature T/NK cell, and no other specification (NOS; 42.3%, 15.8%, 14.1%, and 27.8%, respectively). In both regions, the overall incidence rates were similar (central=5.3, 95% confidence interval [CI], 4.6-6.1 vs. southern=6.3, 95% CI, 4.6-8.4); also, there were no differences by types (precursor cell LNH, 2.3 vs. 2.5; mature B cell, 0.9 vs. 0.8; mature T/NK cells, 0.8 vs. 0.8; and NOS, 1.4 vs. 2.3). In both regions, a decreasing trend was found (central= −0.17%, 95% CI, −0.03 to −0.3, P=0.04; southern= −0.32%, 95% CI, −0.07 to −0.57, P=0.02), with major reduction of NHL NOS from 1996 to 2000. In both regions, men predominated (2.1:1). Conclusions: Socioeconomic status did not influence the incidence rates of NHL. In this study, we found a reduction of NHL NOS, possibly due to better typing.

Linfoma de Burkitt nasofaríngeo

“…En el ámbito mundial se reporta un pico de incidencia a los 10 años y con predominio masculino (2:1). [1][2][3][4] Dentro de las características clínicas del linfoma de Burkitt variante esporádica, lo más común es su presentación abdominal (50%) o en médula ósea. Es infrecuente su localización en cabeza y cuello, pero de presentarse en dichas zonas, se presentan como adenopatías cervicales, seguido de localización en maxilar, nasofaringe, mandíbula y amígdalas.…”

“…Estas neoplasias son raras en zona de cabeza y cuello (20-30%); en esta región, la principal afectación es ganglionar, pero pueden presentarse en nasofaringe, glándulas salivales y senos paranasales. [2][3][4][5] doi: 10.35366/97174…”