Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature

Sung, Yu-Wen; Lin, Yun-Shan; Chen, Yen‐Ting; Yeh, Lian Shung

doi:10.1016/j.tjog.2022.03.026

Cited by 9 publications

(5 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, serum CA125 levels can increase in a variety of different disorders, both malignant and nonmalignant[8]. Zidan et al reported that almost 45% of lymphoma patients had increased CA125 levels, which was related to advanced disease, a low response rate, and a low survival rate [9][10][11][12]. However, it is vital to note that when CA125 levels are elevated, the rst thing to investigate is epithelial ovarian cancer, with lymphoma serving as a secondary diagnosis [13].…”

Section: Discussionmentioning

confidence: 99%

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

sun,

ma,

Jiang

et al. 2024

Preprint

View full text Add to dashboard Cite

Background Primary DLBCL of the ovary is an uncommon malignant ovarian tumor. Its pathogenesis is unclear. Clinical symptoms and auxiliary exams show little specificity. Diagnosis is difficult before surgery. It is frequently misdiagnosed as other malignant ovarian tumors. Misdiagnosis frequently leads to excessive therapy. Patient presentation A 51-year-old patient with abdominal pain for two months and an abdominal mass for one week was admitted to the hospital. The patient had no vaginal bleeding or fluid; no fever, chills, night sweats, or weight loss; and no obvious medical or family history. When a diagnosis of an ovarian malignant tumor was considered, we performed double adnexectomy plus adnexectomy, hysterectomy, greater omentectomy, and partial peritonectomy. Postoperative pathology revealed DLBCL of the ovary, an anaplastic center-like subtype. The patient subsequently received two cycles of chemotherapy with the R-CHOP regimen. The patient's condition improved after chemotherapy, with no signs of disease progression, and she was considered for continuation of chemotherapy with the original regimen. Conclusions We reviewed the patient’s clinical data and literature to improve practitioners' understanding of the disease and prevent misdiagnosis and overtreatment.

show abstract

Section: Discussionmentioning

confidence: 99%

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

sun,

ma,

Jiang

et al. 2024

Preprint

View full text Add to dashboard Cite

show abstract

“…Some blood tests have diagnostic and even prognostic values. Elevated CA125 and lactate dehydrogenase levels are often correlated with advanced disease, poor therapeutic response, and poor survival [19][20][21][22]. In the series of Zidane et al, 45% of patients with an elevated CA125 level had an estimated five-year overall survival of 50% for low-grade lymphoma and 27% for the aggressive form [19].…”

Section: Discussionmentioning

confidence: 99%

An Extranodal Site of Diffuse Large B-cell Lymphoma Presenting as Ovarian Cancer

Jaouani¹,

Zaimi²,

Jarroudi³

et al. 2023

Cureus

View full text Add to dashboard Cite

Due to its uncommon nature, primary ovarian lymphoma has no clinical particularities and can be confused with other ovarian cancers. It poses a twofold diagnostic and therapeutic challenge. An anatomopathological and immunohistochemical study is the crucial step in the diagnosis. Our case was a 55-year-old woman diagnosed with an Ann Arbor stage II E ovarian non-Hodgkin's lymphoma who initially presented with a painful pelvic mass. This case reflects the major role of an immunohistochemical study in the diagnosis workup, leading to the appropriate management of such rare tumors.

show abstract

“…Elevated CA-125 is often reported in patients with ovarian lymphoma, frequently above the threshold where SGO/ACOG recommends referral to a gynecologic oncologist for surgical evaluation of adnexal mass. ( Sergi et al, 2021 , Sung et al, 2022 , Kumar et al, 2014 ) CA-125 elevation can also be seen in NHL and may be associated with aggressive disease and lower rates of treatment response ( Memar et al, 2015 ). The use of CA-125 as a prognostic marker or for monitoring treatment response in primary ovarian lymphoma has not been described.…”

Section: Discussionmentioning

confidence: 99%

Primary ovarian lymphoma: A case report

Gerrity

Mercadel

Alghamdi

et al. 2023

Gynecologic Oncology Reports

View full text Add to dashboard Cite

Non-Hodgkin's B-cell lymphoma of the ovary: A case report and review of the literature

Cited by 9 publications

References 12 publications

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

Primary ovarian lymphoma misdiagnosed as epithelial carcinoma: a case report and literature review

An Extranodal Site of Diffuse Large B-cell Lymphoma Presenting as Ovarian Cancer

Primary ovarian lymphoma: A case report

Contact Info

Product

Resources

About