Non‐influence of fetal gender on ductus venosus Doppler flow in the first trimester

Teixeira, Luciano; Leite, Jose O; Viegas, Monica; Faria, Marcos; Pires, Monize Cristine de Oliveira; Teixeira, Henrique Couto; Teixeira, RA; Pettersen, Heverton

doi:10.1002/uog.5330

Cited by 6 publications

(2 citation statements)

References 19 publications

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“…Previous work investigated the influence of fetal sex on DV PIV and PVIV during the first trimester. The clinical findings in healthy pregnancies were heterogeneous with DV PIV found to be elevated in females in one study [37] and not statistically different between females and males in another [38]. More recently, the Trial of Umbilical and Fetal Flow in Europe (TRUFFLE) reported assessment of the DV throughout gestation, combined Fig.…”

Section: Discussionmentioning

confidence: 95%

Sex differences in fetal Doppler parameters during gestation

et al. 2021

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Background Fetal sex is known to affect pregnancy outcomes. In current clinical practice, monitoring of fetal well-being is based on Doppler ultrasound measurements of major placental and fetal vessels. The objective of this study was to investigate the effect of fetal sex on Doppler parameters throughout gestation in healthy pregnancy. Methods A prospective study was conducted in 240 pregnant women with ultrasound examinations at a 4-weekly interval between 12 and 38 weeks of gestation. Pulsed Doppler spectra were collected for the umbilical arteries (UAs), middle cerebral artery (MCA), descending abdominal aorta (DAo), and ductus venosus (DV). Linear mixed effects models were used to determine if the pulsatility indices (PIs) of these vessels depended on gestational age and fetal sex. Results While there were no differences in the MCA PI and DV PIV over gestation between female and male fetuses, the trajectory of the UA and DAo PIs differed by fetal sex (p = 0.02 and p = 0.01, respectively). Conclusions Doppler ultrasound parameters were found to be dependent on fetal sex for some vessels and not for others in healthy pregnancies. Further investigations are needed to understand the physiological mechanisms for these sex differences and the relevance for disease processes in pregnancy.

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Section: Discussionmentioning

confidence: 95%

Sex differences in fetal Doppler parameters during gestation

et al. 2021

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“…The papers on uterine artery Doppler prediction of pre‐eclampsia and fetal growth restriction are probably non‐controversial from a safety point of view, because the fetus is not insonated during the Doppler examination. However, among the seven papers on fetal Doppler at 10–14 weeks6–12, only one6 appeared explicitly to fulfil the requirements listed by the Journal Editors in 19995. (We don't know that the others didn't, we just know that they did not obviously do so.)…”

Section: Journal Policy On Publishing Reports Of First‐trimester Doppmentioning

confidence: 99%