Non-Invasive Biomarker in Prostate Carcinoma: A Novel Approach

Dwivedi, Shailendra; Shukla, Kamla Kant; Gupta, Gaurav; Sharma, Praveen

doi:10.1007/s12291-013-0312-5

Cited by 18 publications

(9 citation statements)

References 12 publications

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“…Further, we have also observed association of elevated pro-inflammatory IL-18 levels with disease progression (TNM staging and stages I, II, III, IV) and also elevated in tobacco exposed patients of carcinoma [3,6,7]. Additionally, levels for stages III and IV were significantly higher in all modes except in tobacco chewers of stage III patients, although the levels were higher than stage II.…”

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confidence: 81%

Aggravation of Inflammation by Smokeless Tobacco in Comparison of Smoked Tobacco

et al. 2014

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confidence: 81%

Aggravation of Inflammation by Smokeless Tobacco in Comparison of Smoked Tobacco

et al. 2014

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“…Several studies have shown that the modulation of inflammation by intravenous vitamin C correlated with decrease in tumour marker levels [186][187][188]. Studies conducted on human subjects reported that that plasma vitamin C and dietary intakes of vitamin C are inversely associated with some markers of the acute phase response and haemostasis that have been associated with greater risk of CVD and non-vascular disease.…”

Section: Vitamin C and Immunitymentioning

confidence: 99%

Vitamin C in Disease Prevention and Cure: An Overview

et al. 2013

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The recognition of vitamin C is associated with a history of an unrelenting search for the cause of the ancient haemorrhagic disease scurvy. Isolated in 1928, vitamin C is essential for the development and maintenance of connective tissues. It plays an important role in bone formation, wound healing and the maintenance of healthy gums. Vitamin C plays an important role in a number of metabolic functions including the activation of the B vitamin, folic acid, the conversion of cholesterol to bile acids and the conversion of the amino acid, tryptophan, to the neurotransmitter, serotonin. It is an antioxidant that protects body from free radical damage. It is used as therapeutic agent in many diseases and disorders. Vitamin C protects the immune system, reduces the severity of allergic reactions and helps to fight off infections. However the significance and beneficial effect of vitamin C in respect to human disease such as cancer, atherosclerosis, diabetes, neurodegenerative disease and metal toxicity however remains equivocal. Thus further continuous uninterrupted efforts may open new vistas to understand its significance in disease management.

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“…The AP-1 transcription factor is a regulator of processes essential for normal growth and development as well as carcinogenesis. Similarly, pro-inflammatory and anti-inflammatory interleukin's genotypes and gene expression have established their role in survival of prostate cancer patients [3][4][5]. Thus molecular diagnostics is going to swing the whole paradigm of screening and treatment.…”

Section: Molecular Diagnosis: Present Statusmentioning

confidence: 99%