Non-invasive brain stimulation for fibromyalgia: current trends and future perspectives

Zhang, Jia-Hao; Liang, Jian; Yang, Zhong-Wei

doi:10.3389/fnins.2023.1288765

Cited by 2 publications

(1 citation statement)

References 73 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[137][138][139][140]. TMS has a lower side effect profile than traditional pharmacological treatments, making it an appealing option for patients who cannot tolerate medication [141,142].…”

Section: Discussionmentioning

confidence: 99%

Navigating the Neurobiology of Migraine: From Pathways to Potential Therapies

Tanaka,

Tuka,

Vécsei

2024

Cells

View full text Add to dashboard Cite

show abstract

“…[137][138][139][140]. TMS has a lower side effect profile than traditional pharmacological treatments, making it an appealing option for patients who cannot tolerate medication [141,142].…”

Section: Discussionmentioning

confidence: 99%

Navigating the Neurobiology of Migraine: From Pathways to Potential Therapies

Tanaka,

Tuka,

Vécsei

2024

Cells

View full text Add to dashboard Cite

show abstract

Modulation of neural networks and symptom correlated in fibromyalgia: A randomized double-blind multi-group explanatory clinical trial of home-based transcranial direct current stimulation

Lopes Alves,

Zortea,

Vicuña Serrano

et al. 2024

PLoS ONE

View full text Add to dashboard Cite

Background Transcranial direct current stimulation (tDCS) might modulate neural activity and promote neural plasticity in patients with fibromyalgia (FM). This multi-group randomized clinical trial compared home-based active tDCS (HB-a-tDCS) on the left dorsolateral prefrontal cortex (l-DLPFC) or home-based sham tDCS (HB-s-tDCS), and HB-a-tDCS or HB-s-tDCS on the primary motor cortex (M1) in the connectivity analyses in eight regions of interest (ROIs) across eight resting-state electroencephalography (EEG) frequencies. Methods We included 48 women with FM, aged 30 to 65, randomly assigned to 2:1:2:1 to receive 20 sessions during 20 minutes of HB-a-tDCS 2mA or HB-s-tDCS, over l-DLPFC or M1, respectively. EEG recordings were obtained before and after treatment with eyes open (EO) and eyes closed (EC). Results In the EC condition, comparing pre to post-treatment, the HB-a-tDCS on l-DLPFC decreased the lagged coherence connectivity in the delta frequency band between the right insula and left anterior cingulate cortex (ACC) (t = -3.542, p = .048). The l-DLPFC HB-a-tDCS compared to HB-s-tDCS decreased the lagged coherence connectivity in the delta frequency band between the right insula and left ACC (t = -4.000, p = .017). In the EO condition, the l-DLPFC HB-a-tDCS compared to M1 HB-s-tDCS increased the lagged coherence connectivity between the l-DLPFC and left ACC in the theta band (t = -4.059, p = .048). Regression analysis demonstrated that the HB-a-tDCS effect on the l-DLPFC was positively correlated with sleep quality. On the other hand, the HB-a-tDCS on l-DLPFC and HB-s-tDCS on M1 were positively correlated with pain catastrophizing. Conclusions These results show that HB-a-tDCS affects the neural connectivity between parts of the brain that control pain’s emotional and attentional aspects, which are most noticeable at lower EEG frequencies in a rest state. This effect on neural oscillations could serve as a neural marker associated with its efficacy in alleviating fibromyalgia symptoms. Clinical trial registration identifier [NCT03843203].

show abstract

Non-invasive brain stimulation for fibromyalgia: current trends and future perspectives

Cited by 2 publications

References 73 publications

Navigating the Neurobiology of Migraine: From Pathways to Potential Therapies

Navigating the Neurobiology of Migraine: From Pathways to Potential Therapies

Modulation of neural networks and symptom correlated in fibromyalgia: A randomized double-blind multi-group explanatory clinical trial of home-based transcranial direct current stimulation

Contact Info

Product

Resources

About