Non-invasive Evaluation of Brain Death Caused by Traumatic Brain Injury by Ultrasound Imaging

Abstract

Objectives To investigate the clinical value of non-invasive ultrasound imaging in the evaluation of brain death caused by traumatic brain injury. Methods Thirty-four patients with acute severe traumatic brain injury were admitted to hospital within 48 h after injury. All patients were monitored intracranial pressure, transcranial Doppler, echocardiography examination, collection intracranial pressure, MCA-Vs, MCA-Vd, MCA-Vm, EF, LVMPI, RVMPI and other indicators, and combined with clinical conditions and other related data for comparative study and statistical analysis. Results The blood flow spectrum was characterized by diastolic retrograde blood flow spectrum pattern and nail waveform spectrum shape when the patient had clinical brain death. For the parameters of transcranial Doppler, there were significant differences in MCA-Vm and PI between clinical brain death group and normal control group ( P < 0.05). For the parameters of echocardiography, there were statistically significant differences in EF, LVMPI, and RVMPI between clinical brain death group and normal control group ( P < 0.05). Conclusion Non-invasive dynamic monitoring of cerebral hemodynamics and cardiac function parameters in patients with severe craniocerebral injury can provide a high accuracy and reliability for the preliminary diagnosis of brain death in patients with severe craniocerebral injury. It is helpful for early evaluation of prognosis and provides effective monitoring methods and guidance for clinical treatment.

Effects of Transcranial Magnetic Stimulation Combined with Computer-Aided Cognitive Training on Cognitive Function of Children with Cerebral Palsy and Dysgnosia

“…Abnormal cerebral blood flow parameters can reflect the severity of brain injury and affect intellectual development [18,19]. According to relevant studies, children with cerebral palsy with cerebral microcirculation disorders have slow cerebral artery blood flow and increased vascular resistance, which further influences dysgnosia [20]. Cerebral blood flow velocity is closely related to changes in local cerebral blood flow.…”

Target temperature management and therapeutic hypothermia in sever neuroprotection for traumatic brain injury: Clinic value and effect on oxidative stress

“…Group In the middle and late 20th century, foreign neurologists used ice cubes and cryogenic beds and infusion of medicine to make patients hibernate and reduce their temperature to 32°C to 35°C to slow down the development of the disease and strive for treatment time. [17] It has been recorded those dozens of hospitals in the world have used this kind of treatment like hypothermic hibernation for more than 100 patients with STBI. [18,19] Most of the doctors involved in the study hold that lowering the temperature of patients can promote the recovery of severe TBI.…”