Non-Invasive Liver Fibrosis Scores Are Associated With Contrast-Associated Acute Kidney Injury in Patients Undergoing Elective Percutaneous Coronary Intervention

He, Hongtao; You, Zhebin; Zhang, Sicheng; Lin, Xiaoxi; Luo, Manqing; Lin, Muqing; Zhang, Liwei; Lin, Kaiyang; Guo, Yujin

doi:10.1177/00033197221105745

Cited by 6 publications

(10 citation statements)

References 47 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…De Ritis ratio is a readily available marker of liver disease 2 . An association of De Ritis ratio with an increased risk of mortality has been reported in patients with acute myocardial infarction, 15,16 type 2 diabetes, 27 arterial hypertension, 28 and contrast‐induced acute kidney injury after elective PCI 29 . So far, only one study (a retrospective cohort of 203 patients with stable CAD analysed over a mean follow‐up of 749 days) has assessed the association between De Ritis ratio and mortality in patients with stable CAD after elective PCI 17 .…”

Section: Discussionmentioning

confidence: 97%

“…2 An association of De Ritis ratio with an increased risk of mortality has been reported in patients with acute myocardial infarction, 15,16 type 2 diabetes, 27 arterial hypertension, 28 and contrast-induced acute kidney injury after elective PCI. 29 So far, only one study (a retrospective cohort of 203 patients with stable CAD analysed over a mean follow-up of 749 days) has assessed the association between De Ritis ratio and mortality in patients with stable CAD after elective PCI. 17 In this study, a De Ritis ratio of ≥1.4 was associated with approximately threefold higher adjusted hazard for all-cause mortality compared with patients in the lower De Ritis ratio.…”

Section: F I G U R E 1 Kaplan-meier Curves Of Mortality Hr Hazard Ratiomentioning

confidence: 99%

See 1 more Smart Citation

De Ritis ratio and long‐term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention

Ndrepepa

Holdenrieder

Kastrati

2023

Eur J Clin Investigation

View full text Add to dashboard Cite

Background:The association of aspartate aminotransferase to alanine aminotransferase ratio (De Ritis ratio) with clinical outcomes in patients with chronic coronary syndromes (CCS) remains unclear. This study aims to assess the association of De Ritis ratio with adverse cardiovascular events in patients with CCS. Materials and Methods:The study included 5020 patients with CCS undergoing percutaneous coronary intervention. Patients were categorized into groups according to tertiles of the De Ritis ratio: tertile 1 (De Ritis ratio: <.75; n = 1688 patients), tertile 2 (De Ritis ratio: .75-1.08; n = 1666 patients) and tertile 3 (De Ritis ratio: >1.08; n = 1666 patients). The primary endpoint was 3-year mortality.Results: At 3 years, there were 384 deaths, 176 myocardial infarctions and 61 strokes. In groups with De Ritis in the 1st, 2nd and 3rd tertiles, deaths occurred in 5.0%, 7.5% and 14.5% of the patients, respectively (adjusted hazard ratio = 1.09, 95% confidence interval [1.06-1.12], p < .001); myocardial infarctions occurred in 2.6%, 3.5% and 5.1% of the patients, respectively (p < .001); strokes occurred in 1.0%, 1.2% and 1.9% of the patients, respectively (p = .030); bleeding at 30 days (n = 112) occurred in 1.4%, 1.6% and 3.7% of the patients, respectively (p < .001).The C-statistic of the Cox proportional hazards model for all-cause mortality with baseline data without the De Ritis ratio was .815 [.794-.836] and .818 [.797-.838] after the inclusion of the De Ritis ratio (delta C-statistic = .003; p = .005). Conclusions:In patients with CCS undergoing percutaneous coronary intervention, an elevated De Ritis ratio was associated with long-term major adverse cardiovascular events. K E Y W O R D S alanine aminotransferase, aspartate aminotransferase, De Ritis ratio, elective PCI, MACE, prognosisHow to cite this article: Ndrepepa G, Holdenrieder S, Kastrati A. De Ritis ratio and long-term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention.

show abstract

Section: Discussionmentioning

confidence: 97%

Section: F I G U R E 1 Kaplan-meier Curves Of Mortality Hr Hazard Ratiomentioning

confidence: 99%

De Ritis ratio and long‐term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention

Ndrepepa

Holdenrieder

Kastrati

2023

Eur J Clin Investigation

View full text Add to dashboard Cite

show abstract

“…In this retrospective study, which included 5627 patients, CIN developed in 353 (6.3%) patients. The preoperatively calculated FIB-4 scores and APRI values were shown to be significantly associated with the development of CIN [ 15 ]. We also found a significant relationship in our study between high FIB-4 scores and APRI values and the development of CIN in patients who had undergone elective EVAR procedures.…”

Section: Discussionmentioning

confidence: 99%

The Roles of Liver Fibrosis Scores and Modified Stress Hyperglycemia Ratio Values in Predicting Contrast-Induced Nephropathy after Elective Endovascular Infrarenal Abdominal Aortic Aneurysm Repair

et al. 2023

View full text Add to dashboard Cite

Endovascular aortic repair (EVAR) methods are higher preferred for the treatment of patients with abdominal aortic aneurysms (AAAs). Various markers, including the neutrophil-lymphocyte ratio, have been used to predict the risk of contrast-induced nephropathy (CIN). In this study, we aimed to investigate the role of fibrosis-4 score (FIB-4), aspartate transaminase to platelet ratio index (APRI), and modified stress hyperglycemia ratio (mSHR) values in predicting CIN. Patients who had undergone elective endovascular infrarenal abdominal aortic aneurysm repair in our clinic between January 2015 and January 2022 were included in this retrospective study. Patients who did not develop contrast-induced nephropathy after the procedure were identified as Group 1, and those who did were referred to as Group 2. A total of 276 patients were included in the study. The two groups were similar in terms of age, gender, body mass index, hypertension, diabetes mellitus, chronic obstructive pulmonary disease, hyperlipidemia, and left ventricular ejection fraction. In Group 2, the FIB-4 score, APRI, and mSHR values were significantly higher (p = 0.008, p < 0.001, and p < 0.001, respectively). In Group 2, the contrast volume and number of packed blood products used (median 1 (1–4) vs. 2 (1–5)) were significantly higher (p = 0.003 and p = 0.012, respectively). In this study, we demonstrated that we may predict the risk of CIN development with preoperatively calculated, noninvasive liver fibrosis scores and mSHR.

show abstract

“…Since clinical features and event rates were similar to other reports, 8,9,[15][16][17]23,24 we believe that our results might be representative and useful in clinical practice beyond the single-center studies previously reported. 16,[25][26][27][28][29][30] Early risk stratification and structured discharge planning of STEMI patients have gained interest in the last years 12,13 and, moreover, through the COVID-19 pandemic. 6 Adoption of this treatment strategy could reduce hospital costs, resource utilization, and enhance patient satisfaction without affecting outcome.…”

Section: Discussionmentioning

confidence: 99%

Applicability of the Zwolle score for selection of very high-risk ST-elevation myocardial infarction patients treated with primary angioplasty

et al. 2022

View full text Add to dashboard Cite

The Zwolle risk score was designed to stratify in-hospital mortality risk of ST-elevation myocardial infarction (STEMI) patients treated with primary percutaneous coronary intervention (pPCI) and for decision-making in the unit where patients are admitted. We assessed the accuracy of Zwolle risk score for in-hospital mortality estimation compared with the GRACE score in all patients (n = 4446) admitted for STEMI in 3 university hospitals. Only one fourth of the patients were classified as high-risk by the Zwolle risk score vs 60% by the GRACE score. In-hospital mortality was 10.6%. A statistically significant increase in in-hospital mortality, adjusted by age, gender, and revascularization, was observed with both scores. The assessment of the optimal cut-off points verified the accuracy of Zwolle score ≥4 as optimal threshold for high-risk categorization. In contrast, GRACE score ≥140 had very low specificity as well as percentage of patients correctly classified; GRACE score ≥175 was fairly better. The reclassification index of the Zwolle score after applying the GRACE score was 35.5%. Selection of high-risk STEMI patients treated with pPCI based on the Zwolle risk score has higher specificity than the GRACE score and might be useful in clinical practice.

show abstract

Non-Invasive Liver Fibrosis Scores Are Associated With Contrast-Associated Acute Kidney Injury in Patients Undergoing Elective Percutaneous Coronary Intervention

Cited by 6 publications

References 47 publications

De Ritis ratio and long‐term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention

De Ritis ratio and long‐term major cardiovascular adverse events in patients undergoing elective percutaneous coronary intervention

The Roles of Liver Fibrosis Scores and Modified Stress Hyperglycemia Ratio Values in Predicting Contrast-Induced Nephropathy after Elective Endovascular Infrarenal Abdominal Aortic Aneurysm Repair

Applicability of the Zwolle score for selection of very high-risk ST-elevation myocardial infarction patients treated with primary angioplasty

Contact Info

Product

Resources

About