Non-invasive microwave hyperthermia for bone cancer treatment using realistic bone models and flexible antenna arrays

Geyikoğlu, M. Dilruba; Çavuşoğlu, Bülent

doi:10.1080/15368378.2021.1965069

Cited by 5 publications

(5 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Examples of available commercial IBDs for different medical purposes are shown in Figure 1. In addition, IBDs are widely used for thermal therapies such as hyperthermia and microwave ablation (MWA) for tumor treatment in the lung [9], liver [10], breast [11], bone [12], prostate [13], and kidney [14]. Those therapies offer various advantages over traditional treatments, including (1) minimal invasiveness: involving incisions of approximately 3 mm, hence the recovery process can be accelerated; (2) effective heating: breaking the hydrogen bonds within the natural structure of proteins, leading to the impairment their functionality and causing cellular destruction [15]; and (3) ease of functionality: particularly for patients who are not surgical removal candidates due to limitations such as multiple tumor sites, tumor located in proximity to critical blood vessels, and tumor size [16].…”

Section: Introductionmentioning

confidence: 99%

A Survey of the Thermal Analysis of Implanted Antennas for Wireless Biomedical Devices

Alemaryeen,

Noghanian

2023

Micromachines

View full text Add to dashboard Cite

Wireless implantable biomedical devices (IBDs) are emerging technologies used to enhance patient treatment and monitoring. The performance of wireless IBDs mainly relies on their antennas. Concerns have emerged regarding the potential of wireless IBDs to unintentionally cause tissue heating, leading to potential harm to surrounding tissue. The previous literature examined temperature estimations and specific absorption rates (SAR) related to IBDs, mainly within the context of thermal therapy applications. Often, these studies consider system parameters such as frequency, input power, and treatment duration without isolating their individual impacts. This paper provides an extensive literature review, focusing on key antenna design parameters affecting heat distribution in IBDs. These parameters encompass antenna design, treatment settings, testing conditions, and thermal modeling. The research highlights that input power has the most significant impact on localized temperature, with operating frequency ranked as the second most influential factor. While emphasizing the importance of understanding tissue heating and optimizing antennas for improved power transfer, these studies also illuminate existing knowledge gaps. Excessive tissue heat can lead to harmful effects such as vaporization, carbonization, and irreversible tissue changes. To ensure patient safety and reduce expenses linked to clinical trials, employing simulation-driven approaches for IBD antenna design and optimization is essential.

show abstract

Section: Introductionmentioning

confidence: 99%

A Survey of the Thermal Analysis of Implanted Antennas for Wireless Biomedical Devices

Alemaryeen,

Noghanian

2023

Micromachines

View full text Add to dashboard Cite

show abstract

“…Moreover, it is clearly seen that microwave antenna structures have many advantages in orthopedic applications due to low energy level 12 . In contrast, Geyikoglu and Cavusoglu have not been investigated bone healing; they treated the bone cancer by non‐invasive microwave hyperthermia technique and also flexible antenna structure is presented 13 . In addition, Bone mineral density has been examined by wide band microwave techniques, since bone mineral density could provide to detect the case of fractures or de‐mineralization in the case of osteoporosis conditions 14 .…”

Section: Introductionmentioning

confidence: 99%

“…This is important to decide operating frequency range in microwave detection of health monitoring. Non‐invasive microwave hyperthermia of bone models of cancer patient‐specific is also studied by utilizing antenna array of which pattern has been formed to sectionally increase the tumor temperature to healing values when keeping temperature of other tissues at body level 13 . It demonstrates that the antennas not only been utilized for detection of healing, but also used to increasing temperature of local tissues.…”

Section: Introductionmentioning

confidence: 99%

“…12 In contrast, Geyikoglu and Cavusoglu have not been investigated bone healing; they treated the bone cancer by noninvasive microwave hyperthermia technique and also flexible antenna structure is presented. 13 In addition, Bone mineral density has been examined by wide band microwave techniques, since bone mineral density could provide to detect the case of fractures or demineralization in the case of osteoporosis conditions. 14 Furthermore, there are many attempts to investigate bone healing period in the literature by different techniques.…”

mentioning

confidence: 99%

“…Non-invasive microwave hyperthermia of bone models of cancer patient-specific is also studied by utilizing antenna array of which pattern has been formed to sectionally increase the tumor temperature to healing values when keeping temperature of other tissues at body level. 13 It demonstrates that the antennas not only been utilized for detection of healing, but also used to increasing temperature of local tissues. Monitoring of bone fracture healing has also been investigated in near field approach of a radio frequency coil-based antenna operating between 410-440 MHz.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Theoretical and experimental sensing of bone healing by microwave approach

Akdoğan

Özkaner

Alkurt

et al. 2022

Int J Imaging Syst Tech

View full text Add to dashboard Cite

A medical imaging system is often required to monitor bone growth or bone healing in patients. X-ray imaging method is one of the most used imaging systems but it affects human health due to the ionizing effect of X-rays on matter. In this paper, authors investigated the healing period of a bone structure by using electromagnetic antennas. Two different design approaches were examined which are the monopole antenna approach and the horn antenna approach with the frequency bands of 4-10 and 3-18 GHz, respectively.According to simulation results of the first scenario, radius change of a circular bone from 1 to 8 mm causes a transmission reduction from À13.5 dB to À20 dB at 7 GHz. In the second scenario, the thickness of the bone changed from 0.05 to 20 mm and the corresponding transmission value is reduced from À5 to À25 dB at 10 GHz of constant frequency. All these two approaches showed that the bone variation with time changes the transmission characteristics of detector antennas at the operating frequencies. In the last step of this study, an experimental measurement is carried out by using two opposite horn antennas and a planar bone structure in microwave laboratory. The measured results are in a good agreement with the simulated results in the second scenario. This study gives an opportunity to determine bone healing periods in medical applications by microwave techniques.

show abstract

Directional microwave heating based on time reversal quantified by information theory

Xu,

Huang,

et al. 2023

International Journal of Heat and Mass Transfer

View full text Add to dashboard Cite

Non-invasive microwave hyperthermia for bone cancer treatment using realistic bone models and flexible antenna arrays

Cited by 5 publications

References 17 publications

A Survey of the Thermal Analysis of Implanted Antennas for Wireless Biomedical Devices

A Survey of the Thermal Analysis of Implanted Antennas for Wireless Biomedical Devices

Theoretical and experimental sensing of bone healing by microwave approach

Directional microwave heating based on time reversal quantified by information theory

Contact Info

Product

Resources

About