2024
DOI: 10.3389/fmed.2024.1254467
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Non-invasive prediction of preeclampsia using the maternal plasma cell-free DNA profile and clinical risk factors

Yan Yu,
Wenqiu Xu,
Sufen Zhang
et al.

Abstract: BackgroundPreeclampsia (PE) is a pregnancy complication defined by new onset hypertension and proteinuria or other maternal organ damage after 20 weeks of gestation. Although non-invasive prenatal testing (NIPT) has been widely used to detect fetal chromosomal abnormalities during pregnancy, its performance in combination with maternal risk factors to screen for PE has not been extensively validated. Our aim was to develop and validate classifiers that predict early- or late-onset PE using the maternal plasma … Show more

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