Non-invasive ventilation for respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease in older patients

Balami, Joyce S.; Packham, Stuart; Gosney, Margot

doi:10.1093/ageing/afi211

Cited by 36 publications

(12 citation statements)

References 27 publications

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“…36,37 Compared to the pilot study of La Regina and colleagues, 37 with which we share the variety of etiologies of ARF, in patients with hypercapnic ARF our data indicate a slightly higher success rate (80.9% vs 68.8%), more similar to that reported by Fiorino and colleagues 36 (85%) and also in the English study of Balami 38 (79%). These last two studies, however, are derived from a population of ARF with unique etiology due to COPD and, in the study of Balami, in the presence of HDU.…”

Section: Discussionsupporting

confidence: 82%

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Use and performance of non-invasive ventilation in Internal Medicine ward: a real-life study

Ventrella¹,

Giancola²,

Cappello³

et al. 2015

Ital J Med

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Controlled trials demonstrated efficacy and safety of non-invasive ventilation (NIV) in treatment of acute respiratory failure, initially in Intensive Care Units, then in other care settings (semi-intensive care units, emergency departments, and also in the wards, more often pneumological ones). Few studies have been published about NIV in Italian wards of Internal Medicine with full self-management of NIV by internists in a normal ward setting. We performed a prospective real-life study about the use of NIV in Internal Medicine ward devoid of a critical area of semi-intensive therapy, with the aim of confirming, in this setting, the effectiveness of NIV. During a period of 13 months, 42 patients with hypercapnic respiratory failure of different etiology and acidosis (pH<7.35) were treated by NIV. NIV was successful in 81% of patients. In-hospital mortality was 9.5%. Safety of NIV is demonstrated by the absence of serious complications: only 7 patients showed poor compliance and 2 patients had facial pressure ulcer due to the mask. There were not statistical differences in success rate of NIV according to severity of acidosis at admission (pH<7.25 vs pH>7.25), neither according to the acute physiology and chronic health evaluation II score and the national early warning score, but the modified early warning score only showed statistically significant difference with lower values in the success group: 2.82±1.57 vs 4.13±1.46 (P<0.05). NIV has proven to be effective and safe in Internal Medicine ward.

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Section: Discussionsupporting

confidence: 82%

“…In this, our data coincide with those reported in the three other studies conducted in the Departments of Internal Medicine. [36][37][38] Also if you set the cut-off at pH of 7.20 (instead of 7.25), likewise it does not make any statistically significant difference.…”

Section: Discussionmentioning

confidence: 99%

Use and performance of non-invasive ventilation in Internal Medicine ward: a real-life study

Ventrella¹,

Giancola²,

Cappello³

et al. 2015

Ital J Med

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“…Balami et al investigated the use of bilevel positive pressure ventilation (BiPAP) in patients aged over 65 years and found similar success rates (79%) to other studies which tended to look at its use in younger patients 17. Scala et al studied the effects of co-morbidities on the outcome of NIV in patients with an acute exacerbation of COPD.…”

Section: Resultsmentioning

confidence: 90%

Non-invasive ventilation and continuous positive pressure ventilation in emergency departments: where are we now?

Bolton

Bleetman²

2008

Emergency Medicine Journal

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A number of emergency departments have introduced non-invasive positive pressure ventilation (NIV) and continuous positive airway pressure (CPAP) for patients presenting with acute respiratory failure. It is thought that early non-invasive respiratory support will avoid the need for invasive ventilation in many cases. This literature review studied current knowledge of NIV and CPAP in the acute setting with the aim of creating simple guidelines for hospitals initiating early non-invasive ventilatory support in emergency departments. NIV is effective in reducing intubation and mortality rates in patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) and CPAP is effective in reducing mortality in patients with cardiogenic pulmonary oedema, especially when implemented early. NIV and CPAP were also found to be effective in some other causes of acute respiratory failure. There is a role for non-invasive respiratory support in emergency departments.

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“…The refusal of endotracheal intubation and ICU admission is more likely to occur in this patient subset. In this age group, acute exacerbations of COPD have been successfully treated with NPPV [15,20,21], and the available data suggest a benefit of NPPV use in patients with CPE, pneumonia, or DNI [22].…”

Section: Discussionmentioning

confidence: 99%

Use of noninvasive ventilation on internal wards for elderly patients with limitations to respiratory care: a cohort study

Corral‐Gudino

Jorge-Sánchez

García-Aparicio

et al. 2010

Eur J Clin Investigation

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Non-invasive ventilation for respiratory failure due to acute exacerbations of chronic obstructive pulmonary disease in older patients

Cited by 36 publications

References 27 publications

Use and performance of non-invasive ventilation in Internal Medicine ward: a real-life study

Use and performance of non-invasive ventilation in Internal Medicine ward: a real-life study

Non-invasive ventilation and continuous positive pressure ventilation in emergency departments: where are we now?

Use of noninvasive ventilation on internal wards for elderly patients with limitations to respiratory care: a cohort study

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