Non-invasive ventilation in hypercapnic COPD exacerbation: Predictors of mortality

Background Early prediction of non-invasive ventilation failure by using clinical parameters and scoring systems is a promising strategy for reducing mortality in acute exacerbation of chronic obstructive pulmonary disease patients. Our aim was to assess predictors of non-invasive ventilation failure in acute exacerbation of chronic obstructive pulmonary disease and the prognostic role of mid-regional proadrenomedullin. Results Forty-five patients were enrolled, comprising thirty-six males and nine females with mean age 63.4 ± 9.22 years. Mid-regional proadrenomedullin could not predict non-invasive ventilation outcome, while acute physiology and chronic health evaluation score, blood pH, arterial carbon dioxide and platelet count had predictive value. Conclusion Prediction of non-invasive ventilation outcome in acute exacerbation of chronic obstructive pulmonary disease patients is multifactorial and mid-regional proadrenomedullin alone could not predict this outcome.

show abstract

Mid-regional proadrenomedullin as a potential prognostic factor of NIV outcome in AECOPD

Elnady

Assal

Kandeel

et al. 2023

Beni-Suef Univ J Basic Appl Sci

View full text Add to dashboard Cite

show abstract

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

customersupport@researchsolutions.com

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Made with 💙 for researchers

Part of the Research Solutions Family.

Non-invasive ventilation in hypercapnic COPD exacerbation: Predictors of mortality

Abstract: Background: Long-term survival after non-invasive ventilation (NIV) in patients with chronic obstructive pulmonary disease (COPD) and acute hypercapnic respiratory failure is a significant outcome.

Cited by 1 publication

References 14 publications

Mid-regional proadrenomedullin as a potential prognostic factor of NIV outcome in AECOPD

Mid-regional proadrenomedullin as a potential prognostic factor of NIV outcome in AECOPD

Contact Info

Product

Resources

About