Non-leaching antibacterial cotton fabrics based on lipidated peptides

Opitakorn, Apiradee; Rauytanapanit, Monrawat; Waditee‐Sirisattha, Rungaroon; Praneenararat, Thanit

doi:10.1039/c7ra03565a

Cited by 16 publications

(8 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These fabric finishes are often quoted as more environmentally friendly alternatives to others on the market (Wang & Peng, 2011). They are applied by cross-linking to the fabric (Du et al, 2018;Hassan & Carr, 2019;Cardamone & Martin, 2008), and can be combined with nanoparticle application, which can impart antibacterial properties (Cardamone & Martin, 2008;Opitakorn et al, 2017).…”

Section: Fabric Finishing Solutionsmentioning

confidence: 99%

A review: can waste wool keratin be regenerated as a novel textile fibre via the reduction method?

Lebedytė

Sun

2021

The Journal of The Textile Institute

View full text Add to dashboard Cite

In the mid-twentieth century, natural fibre shortages spurred research into regenerated protein fibres, including research into regenerated wool keratin. Although these materials were soon displaced by outperforming synthetic fibres, today's global shifts towards an eco-friendlier, more environmentally aware, sustainable fashion industry have increased interest into such materials. This paper discusses the theory behind chemically recycling wool (keratin) from textile waste via a mixed solvent system that employs reduction, one of the several possible methods, and then wet spinning of a blended keratin solution to create a novel filament. The scope is to create a high value product that could help close the loop of the wool textile industry. Chemical wool recycling is suggested as a complementary process to the already existing mechanical wool recycling methods, as it can be used for materials that cannot be processed mechanically. It is generally recognised that regenerated wool keratin has poor mechanical stability and if used for textile production would most likely exist in blends with other materials and require post-processing to improve performance. These novel materials could displace some of the currently dominant fibres on the textile market and therefore help mitigate some the negative environmental impacts of the fashion industry, provided they meet ecofriendly credentials in their manufacture and end-of-life. The chemical principles outlined herein can be in many cases applied to other keratinaceous waste streams such as non-edible animal products (horns, hooves), feathers and, importantly, other (non-textile) sources of wool.

show abstract

Section: Fabric Finishing Solutionsmentioning

confidence: 99%

A review: can waste wool keratin be regenerated as a novel textile fibre via the reduction method?

Lebedytė

Sun

2021

The Journal of The Textile Institute

View full text Add to dashboard Cite

show abstract

“…In this study we focused on the peptide sequence Pal-X-Ala-D-Ala-X [44,57] and applied three variations to the cationic residues X, namely Lys, His, and Arg (Table 1). Cationic residues are fundamental to impart antimicrobial properties even to small peptides [24,48]. Lys, Arg, and His are all protonated under physiological conditions.…”

Section: Peptide Designmentioning

confidence: 99%

“…This result is rather surprising as some members of this family are composed of as few as four amino acid residues. Nevertheless, these peptides permeate and disrupt membranes with the same potency of many longer AMPs [48,49].…”

Section: Introductionmentioning

confidence: 99%

Covalent Graft of Lipopeptides and Peptide Dendrimers to Cellulose Fibers

et al. 2019

View full text Add to dashboard Cite

Introduction: Bacterial proliferation in health environments may lead to the development of specific pathologies, but can be highly dangerous under particular conditions, such as during chemotherapy. To limit the spread of infections, it is helpful to use gauzes and clothing containing antibacterial agents. As cotton tissues are widespread in health care environments, in this contribution we report the preparation of cellulose fibers characterized by the covalent attachment of lipopeptides as possible antimicrobial agents. Aim: To covalently link peptides to cotton samples and characterize them. Peptides are expected to preserve the features of the fabrics even after repeated washing and use. Peptides are well tolerated by the human body and do not induce resistance in bacteria. Materials and Methods: A commercially available cotton tissue (specific weight of 150 g/m2, 30 Tex yarn fineness, fabric density of 270/230 threads/10 cm in the warp and weft) was washed with alkali and bleached and died. A piece of this tissue was accurately weighed, washed with methanol (MeOH) and N,N-dimethylformamide (DMF), and air-dried. Upon incubation with epibromohydrin, followed by treatment with Fmoc-NH-CH2CH2-NH2 and Fmoc removal, the peptides were synthesized by incorporating one amino acid at a time, beginning with the formation of an amide bond with the free NH2 of 1,2–diaminoethane. We also linked to the fibers a few peptide dendrimers, because the mechanism of action of these peptides often requires the formation of clusters. We prepared and characterized seven peptide-cotton samples. Results: The new peptide-cotton conjugates were characterized by means of FT-IR spectroscopy and X-ray Photoelectron Spectroscopy (XPS). This latter technique allows for discriminating among different amino acids and thus different peptide-cotton samples. Some samples maintain a pretty good whiteness degree even after peptide functionalization. Interestingly, these samples also display encouraging activities against a Gram positive strain. Conclusions: Potentially antimicrobial lipopeptides can be covalently linked to cotton fabrics, step-by-step. It is also possible to build on the cotton Lys-based dendrimers. XPS is a useful technique to discriminate among different types of nitrogen. Two samples displaying some antibacterial potency did also preserve their whiteness index.

show abstract

“…In spite of the type of bacteria, as-prepared hydrogels show an excellent antibacterial rate of 99.9% when the initial bacterial concentration is 2 × 10 5 CFU/mL . However, the release rate of the physically incorporated antimicrobial agents from hydrogels in vivo is hard to control, which impedes their long-term usage …”

Section: Introductionmentioning

confidence: 99%

“…23 However, the release rate of the physically incorporated antimicrobial agents from hydrogels in vivo is hard to control, which impedes their long-term usage. 24 Cationic polymer containing cationic groups and hydrophobic groups can kill bacteria via a charge interaction, which can disrupt the integrity of the bacteria membrane. 25 Poly(hexamethylene guanidine) (PHMG) is a type of highly water-soluble cationic polymer which can be used to prepare antimicrobial polymeric materials.…”

Section: Introductionmentioning

confidence: 99%

PVA/Poly(hexamethylene guanidine)/Gallic Acid Composite Hydrogel Films and Their Antibacterial Performance

Yang

Wang

Sha

et al. 2021

ACS Appl. Polym. Mater.

View full text Add to dashboard Cite

Carboxylated poly(vinyl alcohol) (PVA-COOH) is prepared by modifying PVA with succinic anhydride. Then, poly(hexamethylene guanidine (PHMG) as a cross-linker and gallic acid (GA) as an antioxidant are added to obtain PVA-based composite hydrogel films (PVA-COOH-PHMG/GA). The as-prepared PVA-based composite films show hydrophilic surfaces, high swelling ratios of 600–700%, low water solubility for PVA-COOH-PHMG samples (about 10%), and good mechanical properties. Importantly, when the initial bacterial concentration is 107 CFU/mL, the antibacterial rate of PVA-based composite films against Escherichia coli and Staphylococcus aureus can reach 99.999%. When the initial bacterial concentration is 108 CFU/mL, the antibacterial rates of these composite films against E. coli and S. aureus can be 99.9999% and 99.988%, respectively. The antibacterial mechanism is also discussed via a live/dead bacteria assay. The cytotoxicity test reveals that the resultant PVA-COOH-PHMG composite hydrogel films without GA have good biocompatibility toward L929 cells, but PVA-COOH-PHMG/GA composite films with addition of GA decrease the cell viability. Interestingly, the PVA-COOH-PHMG/GA composite hydrogel films can scavenge 70% of 1,1-diphenyl-2-picryhydrazyl (DPPH) free radical because of the release of GA, indicating an excellent antioxidant efficiency. It is anticipated that the resultant PVA-based composite hydrogel films with an adequate amount of GA not only possess excellent antibacterial properties but also exhibit a good antioxidant activity. Therefore, they show potential for biomedical field applications as wound dressings.

show abstract

Non-leaching antibacterial cotton fabrics based on lipidated peptides

Abstract: A new set of lipidated peptides was in situ synthesised on cotton surface, resulting in non-leaching surfaces with high antibacterial activities in Gram-negative bacteria. These surfaces were also shown to be non-toxic to mammalian cells.

Cited by 16 publications

References 29 publications

A review: can waste wool keratin be regenerated as a novel textile fibre via the reduction method?

A review: can waste wool keratin be regenerated as a novel textile fibre via the reduction method?

Covalent Graft of Lipopeptides and Peptide Dendrimers to Cellulose Fibers

PVA/Poly(hexamethylene guanidine)/Gallic Acid Composite Hydrogel Films and Their Antibacterial Performance

Contact Info

Product

Resources

About