Let H be a complex Hilbert space, B(H) be the algebra of all bounded linear operators on H and A ⊆ B(H) be a von Neumann algebra without central summands of type I 1 . For arbitrary elements A, B ∈ A, one can define their * -Jordan product in the sense of A ⋄ B = AB + BA * . Let pn(x 1 , x 2 , • • • , xn) be the polynomial defined by n indeterminates x 1 , • • • , xn and their * -Jordan products. In this article, it is shown that a mapping δ : A −→ B(H) satisfies the conditionand only if δ is an additive * -derivation.