Non-localized Mycobacterium avium Lung Disease Successfully Treated with Lobectomy and Chemotherapy

Hamada, Noboru; Kawata, Noriko; Shibayama, Takuo; Makihara, Seiichiro; Tada, Atsuhiko; Soda, Ryo; Takahashi, Kiyoshi

doi:10.2169/internalmedicine.49.2707

Cited by 3 publications

(2 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although the American Thoracic Society guidelines state that surgery is indicated only for patients with a predominantly single lung lesion, 16 a case involving diffuse bilateral lung lesions that was treated successfully by resection of a large cavity has been reported previously. 17 In that case, a diffuse infiltrating shadow in the contralateral lung disappeared after removal of the large cavity. Removal of the main large cavity lesion can decrease the bacterial load, stabilize the patient’s condition, and improve residual disease in conjunction with medical treatment.…”

Section: Discussionmentioning

confidence: 85%

Video-assisted thoracoscopic surgery for nontuberculous mycobacterial infection

Matsuoka

Imanishi

Matsuoka

et al. 2014

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 85%

Video-assisted thoracoscopic surgery for nontuberculous mycobacterial infection

Matsuoka

Imanishi

Matsuoka

et al. 2014

Asian Cardiovasc Thorac Ann

View full text Add to dashboard Cite

show abstract

“…Only five reported cases of non-localized bilateral NTM lung disease were successfully treated with two-stage bilateral resection: all five patients underwent right middle lobectomy and subsequent left lingulectomy (6). In addition, there was one case of bilateral MAC disease that was successfully treated with single lobectomy in combination with chemotherapy (12). However, these papers did not mention performing bronchoscopy when deciding on the indication of surgical treatment.…”

Section: Discussionmentioning

confidence: 99%

Bronchoscopy as a Useful Examination for Determining Surgical Treatment Indications in Refractory <i>Mycobacterium avium</i> Complex Lung Disease Patients with Bilateral Lesions

et al. 2019

View full text Add to dashboard Cite

We herein report three cases of refractory Mycobacterium avium complex (MAC) disease successfully treated surgically despite the MAC lesions being present bilaterally. Of note, although two patients did not present with any respiratory symptom, bronchoscopy clearly revealed a major excretory lesion with a large amount of purulent sputum in all patients. Because an excretory lesion was localized, surgical resection was performed, and the mycobacterial sputum smear became negative in all patients. Bronchoscopy may be a useful examination for detecting major excretory lesions with purulent sputum, which can disseminate to other lobes, and for determining the surgical indications of refractory MAC patients, regardless of the presence of respiratory symptoms.

show abstract