2024
DOI: 10.1007/s12519-024-00853-8
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Non-malignant features of cancer predisposition syndromes manifesting in childhood and adolescence: a guide for the general pediatrician

Michaela Kuhlen,
Andreas B. Weins,
Nicole Stadler
et al.

Abstract: Purpose Cancer predisposition syndromes are genetic disorders that significantly raise the risk of developing malignancies. Although the malignant manifestations of cancer predisposition syndromes are well-studied, recognizing their non-malignant features is crucial for early diagnosis, especially in children and adolescents. Methods A comprehensive literature search was conducted using the PubMed database, focusing on non-malignant manifestations of cance… Show more

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