Non-motor disorders in patients with muscular dystonia

Salouchina, N I; Nodel, M. R.; Толмачева, В. А.

doi:10.17116/jnevro201811809198

Cited by 7 publications

(1 citation statement)

References 100 publications

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“…Боль не только является следствием двигательных нарушений, она также связана с развитием депрессии и тревоги [8]. Распространенность аффективных расстройств при ЦД может доходить до 91,4%, по сравнению с 35% в общей популяции [9,10].…”

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Cervical dystonia: current rehabilitation strategies and methods

Истомина

Miliukhina

Дидур

2020

RJTAO

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Idiopathic cervical dystonia (CD) is a movement disorder that is characterized by sustained or intermittent muscle contractions causing often repetitive movements, fixed postures, or both. This is the most common form of focal dystonia. The lack of highly effective rehabilitation in CD can substantially increase the number of disabled people and/or lead to a significant decrease in the working capacity of young patients. Despite the high social significance of the problem, there are currently insufficient studies of the use of medical and physical rehabilitation methods for CD. Taking into account the complexity, multicomponent pattern, and clinical diversity of CD manifestations, these patients require multidisciplinary treatment and rehabilitation approaches to achieve maximum results. This review discusses rehabilitation strategies and methods in CD, which are based on the modern understanding of the etiology and pathogenesis of the disease. As a supplement to botulinum toxin therapy, a multimodal physiotherapy program, kinesio taping, and special and general strengthening physical exercises are considered, which can assist in correcting the posture, reducing the severity of pain in patients with CD, improving daily activity, and increasing the intervals between botulinum toxin injections and lowering the dose of the drug administered.

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Cervical dystonia: current rehabilitation strategies and methods

Истомина

Miliukhina

Дидур

2020

RJTAO

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The impact of non-motor disorders on the quality of life of patients with cervical muscular dystonia

Nodel

Salouhina

Толмачева

2022

RJTAO

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Cervical dystonia (CD) has a wide range of non-motor (neuropsychiatric, sensory, dyssomnic) disorders. Relationships between dystonia, nonmotor manifestations of the disease and patients quality of life (QoL) require clarification.Objective: to clarify the impact of dystonia, sensory, affective, behavioral disorders, quality of sleep and wakefulness on the quality of life of patients with CD.Patients and methods. We examined 61 patients with CD (mean age – 48.03±11.49 years, mean duration of CD – 4.89±4.05 years). We used Toronto Western Hospital Spasmodic Torticollis Rating Scale (TWSTRS), Cervical Dystonia Quality of Life Questionnaire (CDQ-24, with five subscales: «stigma», «emotional wellbeing», «pain», «activities of daily living», «social/family life»), Spielberger–Khanin Inventory (STAI),Beck Depression Inventory (BDI), Barratt Behavioral Impulsivity (BIS-11), Yale–Brown Obsessive Compulsive Scale (Y-BOCS), Montreal Cognitive Assessment Scale (MoCA), Stroop Test (VST), 12 Word Memory Test, Pittsburgh Sleep Quality Assessment Scale (PSQI), Epworth Sleepiness Scale (ESS).Results and discussion. There was a deterioration in all characteristics of QoL in patients with CD, largely in emotional well-being, stigmatization, pain syndrome (50% change from the maximum CDQ-24 score). A statistically significant moderate correlation was established between the total assessment of QoL and the severity of dystonia (r=0.35; p<0.01), a statistically significant strong correlation between the total assessment of QoL and depression index (r=0.73; p<0.001 ), moderate strength correlation – with indicators of anxiety (r=0.65; p<0.01), obsessivecompulsive disorders (r=0.61; p<0.01), sleep quality (r=0.52; p<0.001), impulsiveness in behavior (r=0.31; p<0.01), weak relationship with the assessment of executive cognitive functions (according to the Stroop test interference index; r=0.24; p<0.01). A statistically significant moderate correlation was found between the assessments of activity in everyday, social/family life and impulsiveness in behavior (r=0.33; p<0.001); between stigma, emotional well-being and an indicator of executive cognitive functions (r=0.3; p<0.05). There were no statistically significant relationships between indicators of affective, cognitive functions, behavioral disorders and the severity of dystonia. There was a moderate correlation between pain score and dystonia severity (r=0.35; p<0.01).Conclusion. The decrease in QoL in patients with CD is largely due to affective, sensory, and behavioral disorders. Diagnosis and appropriate therapy of the non-motor aspects of the disease are required for adequately improvement of QoL of patients.

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