Non-Neoplastic Testicular and Paratesticular Lesions Study from A Remote Indian Island

Gargade, Chitrawati Bal; Deshpande, Archana

doi:10.21276/apalm.2704

Cited by 2 publications

(6 citation statements)

References 12 publications

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“…In our study, 31 to 40 years was the common age group for neoplastic testicular (50%). (Table 1) This was in agreement with various studies Gargade et al 7 Tekumalla et al 13 and Mansi Sharma et al 8 The most common neoplastic Testicular lesion studied in our study was mixed germ cell tumor (75%). (Table 3 ) This is consistent with the study conducted by Sheeja et al 11 The most common neoplastic testicular lesion studied in other studies were mostly seminoma.…”

Section: Comparison Of Spectrum Of Lesions In Testissupporting

confidence: 93%

“…Mostly the presentation was in young patients aged <40 years (67.3%). This was consistent with studies conducted by Gargade et al, 7 Mansi Sharma et al, 8 Hemavathi Reddy et al 9 and Sundari et al, 10 who suggested that the maximum number of cases in their study belonged to <40 years age group.…”

Section: Age Wise Distribution Of Casessupporting

confidence: 91%

“…(Table 3 ) This is consistent with the study conducted by Sheeja et al 11 The most common neoplastic testicular lesion studied in other studies were mostly seminoma. 7,8,12,13 The most common non-neoplastic testicular lesion was torsion testis (27.3%) followed by cryptorchidism (18.2%).Table 3 This is consistent with studies conducted by Gargade et al 7 and Sheeja et al 11 who also reported torsion of testis as commonest non-neoplastic lesion. Other nonneoplastic lesions reported by Tekumalla et al, 13 Gaikwad et al 12 and Mansi Sharma et al 8 were epididymo-orchitis, testicular atrophy, undescended testis respectively.…”

Section: Comparison Of Spectrum Of Lesions In Testissupporting

confidence: 84%

“…Gargade et al, 7 Mansi Sharma et al 8 and Sheeja S. et al 11 also reported that non-neoplastic lesions were more common than neoplastic ones and younger age presentation was also in agreement. However, in contrary to our study, Gaikwad et al 12 and Tekumalla A. et al 13 reported older age presentation of non-neoplastic testicular lesions.…”

Section: Comparison Of Spectrum Of Lesions In Testismentioning

confidence: 76%

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Surgico-pathological analysis of testicular lesions

Vidhale¹,

Upasham²

2021

ACHR

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The primary objective of our study was to identify the different types of histopathological lesions of testes and epididymis occurring in patients admitted in a tertiary care hospital, the objective was also to analyze the spectrum of testicular lesions, our aim was to evaluate the prevalence of testicular malignancies and characterize the tumor based on their histo-morphological features. This was a prospective study of 2 years (October 2018 to October 2020) aggregating a total of 52 cases. The surgical specimens were referred to the pathology department for histopathological analysis. Adetailed preoperative history of every case with regards to age, presenting symptoms, and signs along with personal history were obtained.Also, relevant investigations like serum tumor markers and Ultrasonography findings were analyzed. Postoperatively, the tissue was sent to the histopathology department was studied by proper fixation, gross examination, adequate sampling, and paraffin sections of the same.10% formalin was used to fix the specimen. Some resources suggest the use of Bouin solution for the fixation of testis biopsy specimens. However, the picric acid in the Bouin solution presents challenges for safe handling and disposal due to its explosive potential.Hence, given the available resources in our laboratory setting, formalin was the preferred choice of fixative. We ensured that the specimens came in adequate amount of formalin from the OT with correct labeling.We excluded the autolyzed specimens. The data was noted and quantitative analysis was done.The study was further compared with other previously reported studies. 52 cases were studied and majority of the cases were reported in the age group of 31-40yrs. 65.4% cases were non neoplastic, with testicular torsion being the commonest lesion. Amongthe 23.1% neoplastic cases that were reported, mixed germ cell tumor was the commonest (75%). Non neoplastic lesions are more common than neoplastic lesions. Torsion testis was the commonest indication for orchidectomy in younger age group. Despite newer techniques in imaging and tumor marker assays the diagnosis of testicular lesions is primarily dependent upon histopathological examination.

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Section: Comparison Of Spectrum Of Lesions In Testissupporting

confidence: 93%

Section: Age Wise Distribution Of Casessupporting

confidence: 91%

Section: Comparison Of Spectrum Of Lesions In Testissupporting

confidence: 84%

Section: Comparison Of Spectrum Of Lesions In Testismentioning

confidence: 76%

See 2 more Smart Citations

Surgico-pathological analysis of testicular lesions

Vidhale¹,

Upasham²

2021

ACHR

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“…From benign congenital diseases to life-threatening cancers and acute surgical emergencies, testicular and paratesticular lesions can represent a wide spectrum of medical difficulties. 1 These lesions affect people of all ages, with scrotal swelling and pain being the most common In the absence of epididymitis, orchitis manifests as testicular swelling and pain. The onset is usually abrupt and might be unilateral or bilateral in nature.…”

Section: Introductionmentioning

confidence: 99%

Interesting case series on distinct histopathological findings of six cases of epididymo-orchitis

Jaju¹,

Sangeetha

Garg³

et al. 2023

PJMS

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Several clinicopathological illnesses impact the testis and paratesticular area, which are divided into non-neoplastic and neoplastic diseases. Despite the availability of imaging and tumor marker testing, histopathological examination is the primary method for diagnosing testicular lesions. Common indications of orchidectomy for non-neoplastic lesions are cryptorchidism, epididymitis and testicular torsion. Few non- neoplastic lesions present as mimickers of neoplasm with commonest being granulomatous orchitis and AFB positivity detected only in 2.1% of cases with bilateral presentation being rarest. We report here a series of six cases of epididymo-orchitis to discuss the histopathological spectrum with varied etiologies. Age of the patients ranged between 33-65yr old males. Amongst six cases, two of them were clinically and radiologically suspected as neoplastic lesions, which were histopathologically diagnosed as granulomatous epididymo-orchitis with one among it showing strong positivity for AFB, and two cases as testicular torsion with orchitis and one of the case was diagnosed as cryptorchid testis with foci of atypical germ cell and last case was reported as mild non-specific orchitis, for surgical castration. In this study, we also noted unilateral presentation being the commonest, specifically of Right side. Knowledge of histopathological spectrum of epididymo-orchitis is of prime importance to detect underlying specific etiology for targeted therapy and prevent undue orchidectomy.In this study, two cases which were clinically suspected as neoplastic lesions, were confirmed as granulomatous epididymo-orchitis on histopathological examination with one case showing strong AFB positivity.In this study, we noted late presentation (5th decade) of cryptorchidism with some atypical germ cells which are forerunner of malignancy.

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Non-Neoplastic Testicular and Paratesticular Lesions Study from A Remote Indian Island

Cited by 2 publications

References 12 publications

Surgico-pathological analysis of testicular lesions

Surgico-pathological analysis of testicular lesions

Interesting case series on distinct histopathological findings of six cases of epididymo-orchitis

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