Non-opioid anesthetic drug abuse among anesthesia care providers: a narrative review

Zuleta-Alarcon, Alix; Coffman, J.C.; Soghomonyan, Suren; Papadimos, Thomas J.; Bergese, Sergio D.; Moran, Kenneth R.

doi:10.1007/s12630-016-0698-7

Cited by 10 publications

(4 citation statements)

References 92 publications

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“…Cross-sectional and cohort studies involving health workers addicted to these substances indicated that the course of addiction is fast, social and occupational activities are abandoned or reduced due to the use of these substances, significant physical injuries are present due to the intoxication and mortality rates due to acute intoxication and respiratory depression are high. (31)(32) Another characteristic evidenced in this study was illegal substance consumption among the nurses, the most self-reported substances being marihuana and cocaine. This result is supported in the literature, which indicates marihuana as the most consumed illegal drug in the world among young people and adults.…”

Section: Discussionmentioning

confidence: 73%

Ambiente ocupacional e o consumo de substâncias psicoativas entre enfermeiros

et al. 2017

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Objective: To analyze the relation between the work environment and psychoactive substance consumption among hospital nurses. Methods: Cross-sectional and descriptive study, involving nurses from three public hospitals in a city in the South of Brazil, being two medium-complexity and one high-complexity institution. The study population consisted of 221 nurses. Based on this figure, the stratified sample size was calculated, considering a 50% proportion, 95% confidence level and 5% maximum error, resulting in a minimum number of 175 participants. Through proportional stratification per institution, a minimum of 103 high-complexity nurses was defined, as well as 36 nurses from each medium-complexity institution. The following inclusion criteria were adopted: having worked at the institution for at least one year and not being on leave. The data were collected between October 2015 and April 2016. In the data collection, sociodemographic and occupational information, the Nursing Work Index -Revised and the Alcohol, Smoking and Substance Involvement Screening Test. The data were analyzed in the software Statistical Package for Social Sciences, version 20.0. Initially, the normality was verified by means of the Kolmogorov-Smirnov test. Descriptive analyses were developed by absolute and relative frequencies for the categorical variables; and medians and dispersion measures for the numerical variables. Results: Alcohol, tobacco and sedatives were the most consumed substances. The monthly income was positively correlated with alcohol consumption among nurses at the medium-complexity hospitals (p=0.01). At the high-complexity hospital, alcohol consumption was negatively correlated with the physician-nurse index (p=0.03). Autonomy, physician-nurse index and organizational support were negatively correlated with the use of sedatives (p<0.01; p<0.01; p=0.02, respectively). Conclusion: The more negative the nurse's work environment, mainly in the relation with physicians, organizational support and autonomy, the greater the consumption of psychoactive substances. ResumoObjetivo: Analisar a relação entre o ambiente de trabalho e o consumo de substâncias psicoativas entre enfermeiros hospitalares. Métodos: Estudo transversal e descritivo, realizado com enfermeiros de três instituições hospitalares públicas localizados em um município da Região Sul do Brasil, sendo duas de média complexidade e uma de alta complexidade. A população deste estudo foi composta por 221 enfermeiros. Com base nesse número, calculou-se o tamanho amostral por estratos, considerando-se a proporção de 50%, nível de confiança de 95% e erro máximo de 5%, o que resultou no número mínimo de 175 participantes. Mediante a estratificação proporcional por instituição definiu-se o mínimo de 103 enfermeiros da alta complexidade e 36 de cada instituição de média complexidade. Adotou-se como critérios de inclusão: trabalhar na instituição há pelo menos um ano e não estar afastado por licença. A coleta de dados foi realizada entre outubro de 2015 e abril de 2...

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Section: Discussionmentioning

confidence: 73%

Ambiente ocupacional e o consumo de substâncias psicoativas entre enfermeiros

et al. 2017

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“…Zu den am häufigsten genannten Anästhetika dieser Klasse gehören Propofol, Benzodiazepine, Ketamin und die inhalativen Mittel. Unter Anästhesisten wurde die Häufigkeit des Missbrauchs von Narkose-mitteln auf 1,0 % bei den Fachärzten und 1,6 % bei den Assistenzärzten geschätzt [128]. [38].…”

Section: Substanzmissbrauchunclassified

175 Jahre Anästhesie und Narkose – Auf dem Weg zu einem „Menschenrecht auf Ohnmacht“

2021

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Leiter des Zentrum für EthikinderMedizinamAgaplesionMarkusKrankenhaus, Frankfurt a. M. und Honorarprofessor an der Justus-Liebig-Universität, Gießen QR-Code scannen & Beitrag online lesen Zusammenfassung Der "Äthertag", ein Schlüsselmoment in der Geschichte der Menschheit, jährt sich am 16. Oktober 2021 zum 175. Mal. Nachdem der Zahnarzt William T. G. Morton in Boston die erste erfolgreiche öffentliche Äthernarkose gegeben hatte, schien es von nun an möglich, Menschen mit vertretbarem Risiko vor Schmerz zu bewahren und gleichzeitig durch die Induktion von Bewusstlosigkeit vor psychischen Folgeschäden zu schützen. Der Philosoph Peter Sloterdijk spricht von einem "Recht auf Nicht-Dabei-Sein-Müssen", das die Anästhesie dem Menschen seit 1846 ermöglicht, und leitet daraus "gewissermaßen ein Menschenrecht auf Ohnmacht" ab. Die Umsetzung dieser Idee liegt jedoch in weiter Ferne. Zum einen fehlt in vielen Ländern in großer Zahl qualifiziertes Personal, um selbst Narkosen für lebensnotwendige Operationen durchführen zu können. Zum anderen ist über Jahrzehnte klar geworden, dass die Anästhesie für die Menschheit nicht nur segensreich ist, sondern auch ihre "dunkle Seite" zeigen kann: Substanzmissbrauch, Einsatz von Anästhetika bei Folterungen und Hinrichtungen. Zudem ist der Stellenwert der Anästhetika bei Wiederbelebungsmaßnahmen, in der Palliativmedizin und zur Erleichterung von Hinrichtungen unklar oder umstritten. Letztlich sind auch die erforderlichen förmlichen Schritte zur (völker)rechtlichen Anerkennung eines "Menschenrechts auf Ohnmacht" bislang nicht vollzogen worden.

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“…The characteristics of addiction are compulsively seeking and taking drugs, loss of control when limiting intake, and negative emotions (such as irritability, anxiety, and dysphoria) when drugs are unavailable [ 3 , 4 ]. Although opioids have been reported to be the most abused anesthesia medication, the trend of non-opioid anesthetics abuse has become increasingly severe in recent years [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

“…The non-opioid anesthetics have gradually become a significant cause of addiction, death, and career termination [ 6 ]. Recently, a retrospective study among anesthesiologists and nurse anesthetists in Australia and New Zealand shows that the pattern of drug abuse has changed compared with that before.…”

Section: Introductionmentioning

confidence: 99%

Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism

Deng,

Wu,

Gao

et al. 2023

Brain Sciences

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Drug addiction is one of the major worldwide health problems, which will have serious adverse consequences on human health and significantly burden the social economy and public health. Drug abuse is more common in anesthesiologists than in the general population because of their easier access to controlled substances. Although opioids have been generally considered the most commonly abused drugs among anesthesiologists and nurse anesthetists, the abuse of non-opioid anesthetics has been increasingly severe in recent years. The purpose of this review is to provide an overview of the clinical situation and potential molecular mechanisms of non-opioid anesthetics addiction. This review incorporates the clinical and biomolecular evidence supporting the abuse potential of non-opioid anesthetics and the foreseeable mechanism causing the non-opioid anesthetics addiction phenotypes, promoting a better understanding of its pathogenesis and helping to find effective preventive and curative strategies.

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Non-opioid anesthetic drug abuse among anesthesia care providers: a narrative review

Cited by 10 publications

References 92 publications

Ambiente ocupacional e o consumo de substâncias psicoativas entre enfermeiros

Ambiente ocupacional e o consumo de substâncias psicoativas entre enfermeiros

175 Jahre Anästhesie und Narkose – Auf dem Weg zu einem „Menschenrecht auf Ohnmacht“

Non-Opioid Anesthetics Addiction: A Review of Current Situation and Mechanism

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