Non-ossifying fibroma of the spine

Hoeffel, Christine; Golli, M.; Gaucher, H; Fayet-Bonnin, P.

doi:10.1007/bf00174589

Cited by 11 publications

(2 citation statements)

References 2 publications

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“…Benign fibrous histiocytoma (BFH) was first described by Dahlin in 1978 [16]. It was controversial all the time in terms of the difference between non-ossifying fibroma (NOF) and BFH [5,17]. According to previous literatures, BFH was thought to afflict adults between the third and sixth decade, affecting the metaphysis of long bones and in some cases also sacrum, ileum, ribs, and spine.…”

Section: Discussionmentioning

confidence: 99%

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Total vertebral involvement by benign fibrous histiocytoma: A case report and literature review

Yang

Zhong

et al. 2020

Journal of Bone Oncology

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BackgroundBenign fibrous histiocytoma (BFH) is a rare bone tumor, extremely seldom in the spine.MethodsWe present a 52-year-old patient diagnosed with a BFH in the thoracic spine treated with total en bloc spondylectomy. A review of the published literature was also conducted.ResultsNon-ossifying fibroma (NOF) and BFH are named as one tumor called NOF/BFH. A total of 20 spinal BFHs have been previously reported, mainly involving the posterior elements. We present a BFH with total vertebral involvement. Curettage and excision are the main treatment options with limited recurrence.ConclusionsThis is the first total vertebral BFH up to now. Spinal BFH occupies rather low aggressiveness. With rather limited recurrence and malignant degeneration, surgical interventions seem enough for its management.

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Section: Discussionmentioning

confidence: 99%

“…According to the English literature, only one case of spinal NOF [17] and 19 cases of spinal BFH were reported up to now. To learn about the clinical features of spinal BFHs, we reviewed the spinal BFHs in English literatures.…”

Section: Discussionmentioning

confidence: 99%

Total vertebral involvement by benign fibrous histiocytoma: A case report and literature review

Yang

Zhong

et al. 2020

Journal of Bone Oncology

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Phenylketonuria: Dietary and therapeutic challenges

Giovannini

Verduci

Salvatici

et al. 2007

J of Inher Metab Disea

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PKU subjects need special attention in the definition of optimal supplementation of nutrients, which may be insufficient in relation to the type of diet and may otherwise manifest symptoms of deficit. In particular, it is necessary to pay great attention to the long-chain polyunsaturated fatty acid (LC-PUFA) levels in relation to correct development of the central nervous system. On the basis of numerous beneficial effects currently known, a permanent supplementation with LC-PUFAs, in particular with docosahexaenoic acid, should be considered. Moreover, new formulas, Phe-free peptides, and 'modulated' amino acid preparations might help in preventing nutritional deficiencies and imbalances, with the ultimate aim of improving growth. New strategies--such as supply of tetrahydrobiopterin--need to be optimized in terms of targets, patients and expected outcomes.

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What we know that could influence future treatment of phenylketonuria

Sarkissian

Gámez

Scriver

2008

J of Inher Metab Disea

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Phenylketonuria (PKU), a Mendelian autosomal recessive phenotype (OMIM 261600), is an inborn error of metabolism that can result in impaired postnatal cognitive development. The phenotypic outcome is multifactorial in origin, based both in nature, the mutations in the gene encoding the L-phenylalanine hydroxylase enzyme, and nurture, the nutritional experience introducing L-phenylalanine into the diet. The PKU story contains many messages including a framework to appreciate the complexity of this disease where phenotype reflects both locus-specific and genomic components. This knowledge is now being applied in the development of patient-specific therapies.

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Non-ossifying fibroma of the spine

Cited by 11 publications

References 2 publications

Total vertebral involvement by benign fibrous histiocytoma: A case report and literature review

Total vertebral involvement by benign fibrous histiocytoma: A case report and literature review

Phenylketonuria: Dietary and therapeutic challenges

What we know that could influence future treatment of phenylketonuria

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