Non-pharmacological Interventions for Caregivers with Depression and Caregivers of Care Recipients with Co-morbid Depression: Systematic Review and Meta-analysis

Lambert, Sylvie; Brahim, Lydia Ould; McCusker, Jane; Coumoundouros, Chelsea; Audet, Li-Anne; Yaffe⃰, Mark J.; Kayser, John William; Magalhaes, Mona; Belzile, Éric; Turner, N. J.

doi:10.1007/s11606-021-06891-6

Cited by 6 publications

(4 citation statements)

References 66 publications

(148 reference statements)

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“…study showed that intervention characteristics such as face‐to‐face intervention delivery with longer sessions resulted in better coping among caregivers. Other moderators for intervention effectiveness have included professional‐led interventions and individual interventions 18 …”

Section: Introductionmentioning

confidence: 99%

“…Other moderators for intervention effectiveness have included professional-led interventions and individual interventions. 18 To date, three systematic reviews have investigated the benefits of psychosocial interventions for caregivers of patients with cancer, though have not focused on PEI specifically. 17,19,20 In a 2010 metaanalysis of 29 trials of interventions for cancer caregivers, Northouse et al 17 19,20 A recently published review by Cheng 21 focused on PEI found it was effective in reducing anxiety and depression.…”

Section: Introductionmentioning

confidence: 99%

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The effectiveness of psychoeducational interventions on caregiver‐oriented outcomes in caregivers of adult cancer patients: A systematic review and meta‐analysis

et al. 2022

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Objective Cancer caregiving can result in increased psychosocial distress and poor health‐related quality of life (QOL). Psychoeducation has been shown to be effective in enhancing caregiving‐oriented outcomes. A systematic assessment of the overall effect of psychoeducational intervention (PEI) and identification of individual intervention characteristics that may contribute to the effectiveness of PEI is needed. Methods For this meta‐analysis, relevant articles were identified through electronic databases using key search terms and their medical subject heading such as “family caregiver,” “cancer,” and “psychoeducational intervention.” Results Twenty‐eight controlled trials with 3876 participants were included. PEIs had beneficial effect on depression (Standardized Mean Difference [SMD] −0.26; 95% CI = −0.50 to −0.01, p < 0.04), anxiety (SMD −0.41; 95% CI = −0.82 to 0.01, p < 0.05), caregiver burden (SMD −0.84; 95% CI = −1.22 to −0.46, p < 0.0001) and QOL (SMD 0.59, 95% CI 0.24–0.93; p < 0.0009) at the immediate post‐intervention period. At longer‐term follow‐up, the effectiveness of PEI was maintained on QOL (SMD 0.39, 95% CI = −0.00 to −0.77, p < 0.05), and anxiety (SMD −0.57; 95% CI = −1.09 to −0.06, p < 0.03). Moderation analysis showed that intervention characteristics such as studies conducted in high‐income countries, group intervention and studies that focused on specific and mixed cancers explain some of the high variations observed among the included studies. Conclusions PEI may benefit caregivers of cancer patients through the significant effects on caregiver burden, QOL, anxiety, and depression. The findings from the moderation analysis may be important for the design of future interventions.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The effectiveness of psychoeducational interventions on caregiver‐oriented outcomes in caregivers of adult cancer patients: A systematic review and meta‐analysis

et al. 2022

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“…Currently, telephone-based interventions for caregiver self-care are becoming increasingly popular with researchers, but more evidence is needed to verify their effectiveness. RCTs conducted within 3 months indicated the interventions were more effective in reducing informal caregivers’ depressive symptoms than in control groups, which suggests that future RCTs need to pay more attention to the durability of intervention effects with longer follow-up sessions [ 53 ].…”

Section: Discussionmentioning

confidence: 99%

Randomized controlled trials on promoting self-care behaviors among informal caregivers of older patients: a systematic review and meta-analysis

Liu,

Lou,

2024

BMC Geriatr

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Background Informal caregivers of older patients often neglect their self-care, despite the mental and physical health effects of caregiving. Randomized controlled trials (RCTs) on self-care interventions for informal caregivers are lacking, making it difficult to determine effective strategies. This systematic review explored the definition and categories of self-care RCTs for informal caregivers and a meta-analysis was conducted to determine the effectiveness of these interventions. Methods Seven databases (Scopus, Web of Science, MEDLINE, PubMed, ProQuest, CINAHL, and Embase) were searched for articles in English reporting on self-care intervention outcomes for informal caregivers of patients aged 60 years or older. Standardized mean differences (SMD) with 95% confidence intervals (CI) were calculated using a random-effects model. Subgroup, sensitivity, and publication bias analyses were conducted. Results Eighteen studies were included in the systematic review, of which fifteen studies were included in the meta-analysis. RCTs lacked a clear definition of self-care, mainly focused on promoting physical and mental health and individual capacity, and neglected disease prevention. The interventions focused on self-management for health and individual agency, with less attention on health literacy, decision-making capacity, self-monitoring for health status, and linkage to the health system. Meta-analysis results showed that RCTs had a small effect on reducing anxiety (SMD = -0.142, 95% CI [-0.302, 0.017], p = .081) but a significant effect on reducing depression (SMD = -0.214, 95% CI [-0.353, -0.076], p = .002). Country and type of caregiver significantly contributed to the effect of reducing caregivers’ depression in subgroup analysis. Conclusions Studies on caregiver-centered self-care interventions are limited, resulting in a lack of a clear definition and comprehensive intervention. RCTs indicated a small effect on informal caregivers’ mental health, and interventions should consider both mental and physical health. More evidence is needed on the effectiveness of self-care interventions for informal caregivers’ anxiety and physical health.

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“…Although existing literature provides a strong rationale to intervene to address caregiver mental health in India, little evidence exists on how this should be done. Studies from high-income settings generally support the short-term effectiveness of non-pharmacologic interventions for improving the well-being and mental health of caregivers (Yesufu-Udechuku et al, 2015 ; Gabriel et al, 2020 ; Teahan et al, 2020 ; Lambert et al, 2021 ; Wiegelmann et al, 2021 ), including in group settings (Sörensen et al, 2002 ; Cheng and Zhang, 2020 ; Hovadick et al, 2021 ; McLoughlin, 2022 ). However, these studies are of variable quality, and methods for reporting interventions and assessing effectiveness are heterogeneous.…”

Section: Introductionmentioning

confidence: 99%

Does the Nae Umeed group intervention improve mental health and social participation? A pre–post study in Uttarakhand, India

Bailie¹,

Pillai²,

Singh³

et al. 2023

Camb. prisms Glob. ment. health

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There are few evidence-based interventions to support caregiver mental health developed for low-and middle-income countries. Nae Umeed is a community-based group intervention developed with collaboratively with local community health workers in Uttarakhand, India primarily to promote mental wellbeing for caregivers and others. This pre-post study aimed to evaluate whether Nae Umeed improved mental health and social participation for people with mental distress, including caregivers. The intervention consisted of 14 structured group sessions facilitated by community health workers. Among 115 adult participants, 20% were caregivers and 80% were people with disability and other vulnerable community members; 62% had no formal education and 92% were female. Substantial and statistically significant improvements occurred in validated psychometric measures for mental health (12-Item General Health Questionnaire, Patient Health Questionnaire-9) and social participation (Participation Scale). Improvements occurred regardless of caregiver status. This intervention addressed mental health and social participation for marginalised groups that are typically without access to formal mental health care and findings suggest Nae Umeed improved mental health and social participation; however, a controlled community trial would be required to prove causation. Community-based group interventions are a promising approach to improving the mental health of vulnerable groups in South Asia.

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Non-pharmacological Interventions for Caregivers with Depression and Caregivers of Care Recipients with Co-morbid Depression: Systematic Review and Meta-analysis

Cited by 6 publications

References 66 publications

The effectiveness of psychoeducational interventions on caregiver‐oriented outcomes in caregivers of adult cancer patients: A systematic review and meta‐analysis

The effectiveness of psychoeducational interventions on caregiver‐oriented outcomes in caregivers of adult cancer patients: A systematic review and meta‐analysis

Randomized controlled trials on promoting self-care behaviors among informal caregivers of older patients: a systematic review and meta-analysis

Does the Nae Umeed group intervention improve mental health and social participation? A pre–post study in Uttarakhand, India

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