“…Apart from the newly available monoclonal antibodies, for which phase 3 studies and recent meta-analysis have documented promising efficacy [6], the available drugs usually face numerous side-effects and partial satisfaction. These drawbacks have led to the development of numerous non-pharmacological approaches, such as acupuncture [7], chiropractic therapy [8], supraorbital nerve stimulation [9], vagal nerve stimulation [10], greater occipital nerve stimulation [11], psychological interventions [12], and noninvasive brain stimulation [13]. The latter englobes transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS).…”