Non‐pharmacological supportive‐care interventions in acute myeloid leukaemia: a review of randomised controlled trials

Abstract

ADL, activity of daily living; AML, acute myeloid leukaemia; BFI, brief fatigue inventory; EORTC, European organisation for research and treatment of cancer; FACT-F, functional assessment of cancer therapy-fatigue; FVC, forced vital capacity; Gln, glutamine dipeptide; HADS, hospital anxiety and depression scale; H(S)CT, haematopoietic (stem) cell transplantation; HRmax, maximum heart rate; HRR, heart rate reserve; IC induction chemotherapy; IMT, inspiratory muscle training; IV, intravenous; IVC, inspiratory vital capacity; LASA, linear analogue self assessment; LOS, length of stay; MISWT, multistage incremental shuttle walk test; OS, overall survival; POMS, profile of mood states; PST, problem-solving training; QLQ-C30, quality of life questionnaire core 30-item; QoL, quality of life; RCT, randomised controlled trial; RPE, rating of perceived exertion; STS, sit-to-standing; TUG, timed up and go; VO 2 , oxygen uptake; 6MWT, 6-minute walk test.

Analysis of the application value of functional status-based personalized nursing in clinical care for acute leukemia

“…The pathogenesis of this disease is complicated and remains obscure. Relevant studies have implied that the occurrence of this disease may also be related to multiple factors, such as the environment, body immune status in addition to genetic factors [17][18][19]. Chemotherapy is the optimal therapeutic regimen, but chemotherapy drugs often cause adverse side effects such as bone marrow suppression, anemia, nausea and vomiting, fatigue, and organ dysfunction, which seriously threaten the life safety of patients [20].…”

Health professional attitudes and perceptions of prehabilitation and nutrition before haematopoietic cell transplantation

“…23 This has led to increasing interest in its potential role in haematological settings; however, few studies of prehabilitation in HCT exist. 24 Additionally, nutrition interventions within prehabilitation studies have been shown to vary, lack detailed description and are often poorly evaluated. 25 Despite the expansion of prehabilitation services to HCT settings, the prehabilitation services currently being delivered in the UK, nutrition practices pre-HCT and the feasibility of nutritional prehabilitation in this context are all poorly understood.…”

“…Surgical prehabilitation programmes have been shown to reduce hospital length of stay, infection rates and improve quality of life 23 . This has led to increasing interest in its potential role in haematological settings; however, few studies of prehabilitation in HCT exist 24 . Additionally, nutrition interventions within prehabilitation studies have been shown to vary, lack detailed description and are often poorly evaluated 25 .…”