Non-Pharmacological Techniques for Pain Management in Neonates

Golianu, Brenda; Krane, Elliot J.; Seybold, Jeannie; Almgren, Chris; Anand, K.J.S.

doi:10.1053/j.semperi.2007.07.007

Cited by 117 publications

(72 citation statements)

References 61 publications

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“…22 Nonpharmacological therapies, including acupuncture, have been recommended as part of a multidisciplinary approach to managing pain and withdrawal in neonates manging intubated patients in ICUs. 31 Further studies, including larger populations, dose-response studies, as well as randomized blinded studies are greatly needed to further the understanding of acupuncture's efficacy and applicability for managing pain and withdrawal in pediatric intensive care settings.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture Helps Reduce Need for Sedative Medications in Neonates and Infants Undergoing Treatment in the Intensive Care Unit: A Prospective Case Series

GolianuBrenda

SeyboldJeannie

AlmgrenChristina

2014

Medical Acupuncture

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Background: Neonates in intensive care frequently require impressively high doses of opioids and benzodiazepines to manage pain and provide sedation, and discontinuation of these agents often leads to symptoms of withdrawal and increased agitation. Acupuncture, known to attenuate symptoms of pain and withdrawal in adults, may be useful for managing withdrawal symptoms, pain, and agitation in neonates and infants.Objective: This prospective case series of 10 patients was designed as a preliminary pilot study to examine if acupuncture was beneficial and led to reduction of symptoms of withdrawal and agitation in neonates and infants.Methods: The patients with demonstrated symptoms of agitation and withdrawal were treated with an acupuncture protocol consisting of National Acupuncture Detoxification Association acupuncture points and body points (Yin Tang, ST 36, and PC 6.) Results: The patients tolerated acupuncture well and required a decreased amount of prn medication for treating agitation and withdrawal. Conclusions: Acupuncture may be a useful adjunct for managing agitation and withdrawal in neonates and infants in the intensive care unit, and may lead to a decreased need for sedative medications. Further studies, in the form of randomized, blinded controlled trials, are needed to explore acupuncture's efficacy in this setting.

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Section: Discussionmentioning

confidence: 99%

Acupuncture Helps Reduce Need for Sedative Medications in Neonates and Infants Undergoing Treatment in the Intensive Care Unit: A Prospective Case Series

GolianuBrenda

SeyboldJeannie

AlmgrenChristina

2014

Medical Acupuncture

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“…Non-pharmacological measures including environmental and developmental interventions, such as positioning, swaddling and minimal handling, can be effective in reducing chronic distress in babies and may reduce the need for drugs in most cases (Golianu et al 2007 ;Cignacco et al 2010 ;Westrup et al 2007 ). Although the evidence for their use in this group is less convincing than for older children and adults, opioids remain the most extensively studied and used analgesic drugs in ventilated neonates; morphine and fentanyl are the most commonly used drugs.…”

Section: Choice Of Drugmentioning

confidence: 97%

Sedation, Analgesia and Neuromuscular Blockade in the Neonatal ICU

Boyle

Anand

2014

Pediatric and Neonatal Mechanical Ventilation

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“…Swaddling consists of wrapping infants to restrict movements, with modest effects on pain-elicited distress during and after heel sticks in neonates [5]. The pacifying effects of non-nutritive sucking were clearly shown in multiple studies that reported decreased crying, lower heart rates and increased oxygenation in term and preterm neonates during painful procedures like heel sticks and venipuncture [6]. A systematic Cochrane review in 2010 including 44 studies and 3496 infants concluded that sucrose is safe and effective for reducing procedural pain in neonates, although doses ranged widely, from 0.012 to 0.12 g [7].…”

Section: Introductionmentioning

confidence: 98%