Non-Seminomatous Germ Cell Tumor Metastasis to the Jaw: An Imaging Case Report

Abstract

Testicular cancer typically spreads to the lymph nodes, but hematogenous dissemination to distant organs can also occur. Bone metastasis is uncommon and is thought to be a poor prognostic indicator. Jaw metastasis is exceedingly rare but is of great clinical significance, since it may be the first sign of an occult testicular cancer or the first evidence of relapse of a known tumor. Herein, we report the first case describing the imaging and clinical findings of a non-seminomatous germ cell tumor with jaw metastasis at diagnosis.

Systemic anti-cancer treatment in malignant ovarian germ cell tumours (MOGCTs): current management and promising approaches

“…MOGCTs share many characteristics with male testicular germ cell tumours, though MOGCTs can frequently spread to the peritoneum, showing the same pattern as the epithelial ovarian cancer. After appropriate multimodal management, the prognosis is quite good, with 5-year survival exceeding 85% (5)(6)(7)(8). The majority of MOGCTs are diagnosed while confined to the ovary (stage I), and these early-stage tumours can be treated with surgery alone.…”