Non‐small cell lung cancer with gastric metastasis and repeated gastrointestinal bleeding: A rare case report and literature review

Chang, Shih-Chun; Huang, Shih‐Chiang; Tsai, Chun‐Yi; Wang, Shanyu; Liu, Keng-Hao; Yeh, Ta‐Sen; Yeh, Chun‐Nan

doi:10.1111/1759-7714.13815

Cited by 9 publications

(2 citation statements)

References 20 publications

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“…Gastric metastasis from lung cancer seems to be more frequent in smoking men aged over than 45 years old. The mechanism invoked in this atypical site of metastasis is that tumoral cells reach the stomach via swallowing sputum rich in cancer cells, which occurs more likely in smokers who are more susceptible to gastric mucosal damage than non smokers [ 5 ]. Only 2% of all gastrointestinal metastases are symptomatic [ 2 ].…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Gastric Metastasis Originating From Primary Lung Adenocarcinoma: a Case Report

et al. 2023

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Unlike liver and lung, the stomach is rarely a metastatic location for cancers. We report a case of a 62-year-old man known to have lung adenocarcinoma poorly differentiated presented with melena 1 month after diagnosis. Upper endoscopy revealed an ulcerated tumor in the prepyloric antrum. The diagnosis of gastric metastasis from pulmonary cancer was confirmed by the immunohistochemical staining for the thyroid transcriptional factor-1 and the pattern cytokeratine CK7+/CK20-. In conclusion, gastric metastasis from primary lung cancer is a rare phenomenon that every clinician must keep in mind.

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Section: Discussionmentioning

confidence: 99%

A Rare Case of Gastric Metastasis Originating From Primary Lung Adenocarcinoma: a Case Report

et al. 2023

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“…However, the stomach is not a common site for primary lung cancers' metastases, especially compared with brain, liver, adrenal glands, and bones. 74 Yet, the expected lifespan after diagnosis of metastasis is found to be relatively low. The median survival time was four months (average 6.8 months) among 16 cases who died.…”

Section: Lung Cancermentioning

confidence: 99%

Metastasis to the stomach: a systematic review

Ibrahimli,

Aliyev,

Majidli

et al. 2023

F1000Res

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Background: This study reviews the literature on gastric metastases (GM) in terms of diagnosis, treatment, and outcomes. The goal of this study was to provide clinicians with a reliable and beneficial source to understand gastric metastases arising from various primary tumors and to present the growing literature in an easily accessible form. Methods: Articles published in English language from implementation of MEDLINE and Cochrane databases until May 2022 were considered for the systematic review. Articles other than English language, letters to the editor, posters, and clinical images were excluded. Hematogenous and lymphogenic metastases were included whereas direct tumoral invasion and seeding were excluded. Articles and abstracts were analyzed and last selection was done after cross-referencing and by use of defined eligibility criteria. Results: In total 1,521 publications were identified and 170 articles were finally included totaling 186 patients with GM. The median age of patients was 62 years. Gynecologic cancer was the most common cancer type causing GM (67 patients), followed by lung cancer (33 patients), renal cancer (20 patients), and melanoma (19 patients). One of the main treatment methods performed for metastasis was resection surgery (n=62), sometimes combined with chemotherapy (ChT) or immunotherapy. ChT was the other most used treatment method (n=78). Also, immunotherapy was amongst the most preferred treatment options after surgery and ChT (n=10). Conclusions: As 172 case reports were screened in the systematic review from different journals, heterogeneity was inevitable. Some articles missed important information such as complete follow-up or clinical information. Moreover, since all of the included articles were case reports quality assessment could not be performed. Among 172 case reports reviewed, resection surgery was performed the most and was sometimes combined with ChT and immunotherapy. Further research about what type of treatment has the best outcomes for patients with gastric metastases is needed.

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Cisplatin/docetaxel/vinorelbine

2021

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Non‐small cell lung cancer with gastric metastasis and repeated gastrointestinal bleeding: A rare case report and literature review

Cited by 9 publications

References 20 publications

A Rare Case of Gastric Metastasis Originating From Primary Lung Adenocarcinoma: a Case Report

A Rare Case of Gastric Metastasis Originating From Primary Lung Adenocarcinoma: a Case Report

Metastasis to the stomach: a systematic review

Cisplatin/docetaxel/vinorelbine

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