In this plenary talk, we review the status of non-standard neutrino interactions (NSIs). First, we give a brief introduction to neutrino flavor transitions with NSIs based on the standard paradigm of neutrino oscillations. Then, we discuss alternative scenarios for neutrino flavor transitions such as neutrino decoherence, neutrino decay, and NSIs. Second, we investigate NSIs with three neutrino flavors. In general, we introduce production and detection NSIs, including the so-called zero-distance effect, and matter NSIs. In addition, we study mappings and approximate formulas for NSIs. Third, we present a brief account of theoretical models for NSIs. Fourth and most important, we investigate in detail the phenomenology of NSIs based on different types of data from neutrino experiments. Fifth, we give some phenomenological bounds on both matter and production/detection NSIs as well as we present sensitivity and discovery reach of NSIs at future experiments. Finally, we present a summary and state our conclusions.