Non surgical periodontal therapy: An evidence-based perspective

Pal, Debarghya; Nasim, Farha; Chakrabarty, Himadri; Chakraborty, Abhijit

doi:10.18231/j.jdp.2021.012

Cited by 5 publications

(6 citation statements)

References 33 publications

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“…Non-surgical periodontal therapy remains the corner stone of periodontal treatment aiming to remove the etiologic factor, thereby stopping the disease progression and reestablishment of biologically acceptable root surface for healing. So it is not only the first mode of periodontal disease treatment but it also restores tissue health (19,20) .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of the Effect of Topically Applied Probiotics on Interleukin-10 and Osteoprotegerin as an Adjunctive Treatment of Stage І and П Grade A Periodontitis Cases

Edrees,

Nasr,

Mowafy

et al. 2023

Al-Azhar Assiut Dental Journal

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Aim: the use of probiotic gel may be considered as beneficial treatment for periodontitis. This study was directed to evaluate the possible effect of topically applied probiotics on Interleukin-10 (IL-10) and osteoprotegerin (OPG) combined with scaling and root planning (SRP) in treatment of stage І and П grade A periodontitis. Subjects and Methods: 18 female patients were divided randomly into two equal groups. Group I (PG): received SRP combined with topically applied probiotics gel. Group II(CG): received SRP only. All patients were received phase I periodontal therapy. Then all patients were evaluated clinically and biochemically at base line, one month and three months after periodontal therapy Results recorded, tabulated and statistically analyzed using SPSS (statistical package for social sciences). Results: Clinical parameters such as plaque index (PI), gingival index (GI), probing pocket depth (PPD) and clinical attachment level (CAL) were evaluated. In all groups there was a significant reduction regarding the clinical parameters. There was insignificant better results regarding PI and GI in group I. while, there was significant better results regarding PPD and CAL in group I than group II. OPG levels showed insignificant better results in PG than CG but IL-10 levels showed significant better results in PG over time than CG. Conclusion: Adjunctive topically applied probiotic gel exhibited anti inflammatory effect through the significant expression of IL-10 after treatment of stage I and II grade A periodontitis patients. On the other hand seemed to be non significantly improve the bone formation through the limited expression of OPG

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Section: Discussionmentioning

confidence: 99%

Evaluation of the Effect of Topically Applied Probiotics on Interleukin-10 and Osteoprotegerin as an Adjunctive Treatment of Stage І and П Grade A Periodontitis Cases

Edrees,

Nasr,

Mowafy

et al. 2023

Al-Azhar Assiut Dental Journal

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“…Active periodontal therapy (APT) represents the totality of conventional treatment approaches, which includes oral care recommendations and eradication of bacteria, accompanied by additional antimicrobial treatment [1][2][3]. Together with the elimination of risk Medicina 2022, 58, 866 2 of 12 factors, ultrasonic and manual scaling procedures play an essential role in the context of APT, being responsible for achieving stability of the periodontal status [1][2][3]. APT aims to set the parameters for preventing periodontal deterioration and minimization of deep periodontal pockets and implicitly for tooth and periodontal attachment preservation [3].…”

Section: Introductionmentioning

confidence: 99%

“…It is well-known that periodontal disease is determined by the accumulation of microbial biofilms, which will initiate the formation of periodontal pockets and clinical attachment loss [ 1 ]. The first therapy that is indicated in a periodontitis patient is the non-surgical periodontal therapy [ 2 ]. The purpose of the non-surgical therapy is to provide the elimination of radicular microorganisms and endotoxins by eliminating the supra- and subgingival plaque deposits in order to obtain periodontal healing [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…The first therapy that is indicated in a periodontitis patient is the non-surgical periodontal therapy [ 2 ]. The purpose of the non-surgical therapy is to provide the elimination of radicular microorganisms and endotoxins by eliminating the supra- and subgingival plaque deposits in order to obtain periodontal healing [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

“…Active periodontal therapy (APT) represents the totality of conventional treatment approaches, which includes oral care recommendations and eradication of bacteria, accompanied by additional antimicrobial treatment [ 1 , 2 , 3 ]. Together with the elimination of risk factors, ultrasonic and manual scaling procedures play an essential role in the context of APT, being responsible for achieving stability of the periodontal status [ 1 , 2 , 3 ]. APT aims to set the parameters for preventing periodontal deterioration and minimization of deep periodontal pockets and implicitly for tooth and periodontal attachment preservation [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Effectiveness and Clinical Performance of Erythritol Air-Polishing in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials

et al. 2022

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Background and objectives: The purpose of the present systematic review was to analyze the effectiveness of erythritol-based air-polishing in non-surgical periodontal therapy. Materials and methods: The protocol details were registered in the PROSPERO database (CRD42021267261). This review was conducted under the PRISMA guidelines. The electronic search was performed in PubMed, Scopus, and Web of Science databases to find relevant clinical trials published until January 2022. The inclusion criteria consisted of human clinical trials which reported the use of non-surgical periodontal treatment and erythritol air-polishing compared to non-surgical periodontal treatment alone in patients with good systemic health requiring treatment for periodontal disease. Results: 810 studies were imported into the Covidence Platform. Of these, seven clinical trials met the inclusion criteria. In active periodontal therapy, for PD (probing depth), CAL (clinical attachment level), and BOP (bleeding on probing), no statistical significance was achieved at 6 months follow-up. In supportive periodontal therapy for PD, CAL, and BOP, no statistical significance was achieved at 3 months follow-up. Conclusions: The findings suggest that erythritol air-polishing powder did not determine superior improvements of periodontal parameters compared to other non-surgical periodontal therapies. Future randomized clinical trials (RCTs) with calibrated protocols for diagnosis, therapeutic approaches, and longer follow-up are needed to draw a clear conclusion about the efficiency of erythritol air-polishing powder.

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IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis

Hassan,

Abdelkawy,

Shaker

et al. 2024

Clin Oral Invest

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Objectives This research was performed to investigate if there is a role for IL-39 in immunopathogenesis of both systemically healthy and diabetic periodontitis patients. Additionally, to explore if we can consider IL-39 and IL-35 as biomarkers for periodontitis activity. Materials and methods A total of 38 periodontitis patients and 19 control volunteers were included in our study. The periodontitis patients were divided equally into (Group I), 19 patients with stage III grade C periodontitis with diabetes mellitus and (Group II), 19 patients with stage III grade B periodontitis and systemically healthy. Gingival crevicular fluid levels of each interleukin were measured pre- and postoperatively for all periodontitis patients as well as control subjects using ELISA. Results Our study results showed that the highest level for IL-39 was in diabetic periodontitis patients that decreased significantly postoperatively. However, the highest level for IL-35 was revealed in control group while the lowest value was registered in diabetic periodontitis patients and statistically increased after periodontal treatment. Conclusions Based on the results of our research, both investigated biomarkers may have a potent role in pathogenesis of periodontitis. Clinical relevance We could consider both interleukins as accurate diagnostic markers for periodontitis patients, regardless of diabetes mellitus association, as well as promising markers that can aid in the prevention and treatment of periodontitis patients worldwide.

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Non surgical periodontal therapy: An evidence-based perspective

Cited by 5 publications

References 33 publications

Evaluation of the Effect of Topically Applied Probiotics on Interleukin-10 and Osteoprotegerin as an Adjunctive Treatment of Stage І and П Grade A Periodontitis Cases

Evaluation of the Effect of Topically Applied Probiotics on Interleukin-10 and Osteoprotegerin as an Adjunctive Treatment of Stage І and П Grade A Periodontitis Cases

Effectiveness and Clinical Performance of Erythritol Air-Polishing in Non-Surgical Periodontal Therapy: A Systematic Review of Randomized Clinical Trials

IL-39 and IL-35 gingival crevicular fluid levels in diabetic patients with generalized periodontitis

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