Non-Toxic Fumigation and Alternative Control Techniques Against Fungal Colonization for Preserving Archaeological Oil Painting

Novel eco-friendly [1,2,4]triazolo[3,4-a]isoquinoline chalcone derivatives efficiency against fungal deterioration of ancient Egyptian mummy cartonnage, Egypt

“…The microbial examination of the tested mummy cartonnage showed that the presence of fungal growth on the paint layer is less frequent than on the fabric layer, which causes serious damage to the mummy. Brittleness and deep cracks were observed as result of fungal damage to archeological oil painting object (Geweely 2006 ).…”

New data on relevant ancient Egyptian wooden artifacts: Identification of wooden species and study of the state of conservation with multidisciplinary analyses

“…Investigations of wooden objects from ancient Egypt in museums often revealed a number of different types of biological degradation and non‐biological deterioration processes that have affected the various woods. These include wood decay from various types of fungi including brown and soft rot, as well as a chemical corrosion of wood by salts (Fadl et al, 2013; Geweely, 2006; Giachi et al, 2020).…”

Novel hybrid thiazoles, bis-thiazoles linked to azo-sulfamethoxazole: Synthesis, docking, and antimicrobial activity

“…Infections due to bacteria are growing more frequent over the world, and they have the potential to have a significant impact on health and become the primary cause of disease [ [1] , [2] , [3] ]. Public health is severely threatened globally by the emergence of new microbial strains that are resistant to contemporary antibiotics [ 4 , 5 ].…”

“…The resulting scaffolds may be capable of overcoming drug resistance while also increasing activity and binding affinity [ [38] , [39] , [40] , [41] ]. Based on the aforementioned hypotheses and our continued endeavor towards the synthesis of heterocycles [ [42] , [43] , [44] , [45] , [46] , [47] , [48] , [49] , [50] , [51] , [52] , [53] , [54] , [55] , [56] , [57] , [58] , [59] , [60] , [61] , [62] , [63] , [64] , [65] , [66] , [67] , [68] , [69] , [70] , [71] , [72] ] we report herein the synthesis of some thiazoles, bis(thiazoles), and [ 1 , 2 , 4 ]triazolo[3,4- b ] [ 1 , 3 , 4 ]thiadiazines linked to hydrazinyl- N -(5-methylisoxazol-3-yl)benzenesulfonamide moiety as novel hybrid molecules and evaluation their bioactivities against different bacterial strains and fungal strains; in an attempt to conquer sulfonamide resistance and find novel therapeutic options. Furthermore, the potential binding interactions of the novel compounds with the active sites of different target enzymes were investigated using molecular docking simulations.…”