Non-toxigenic corynebacterium diphtheriae var gravis endocarditis of the aortic valve

McGiffin, David C.; Galbraith, Andrew; Wong, Mae; Burstow, Darryl J.

doi:10.1016/s1328-0163(97)90064-6

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2014

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“…There is precedence for using topical antibiotics in the management of aortic root abscesses in active endocarditis. A patient has been described with a large aortic root abscess that persisted and continued to expand following an aortic valve replacement with an allograft valve and its progression was halted only with the instillation of vancomycin‐impregnated biological sealant. The use of antibiotic‐impregnated sealant in abscess cavities has previously been reported .…”

Section: Commentsmentioning

confidence: 99%

Reconstructing the Infected Aortic Root with Antibiotic Impregnated Biological Glue

2014

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Prosthetic valve dehiscence and persistent infection are two complications following reconstruction of the aortic root in destructive endocarditis. A technique is described involving the principles of aggressive debridement, closure of large abscess cavities with biological material incorporating a slurry of antibiotic-impregnated biological sealant, and replacement of the aortic valve with an aortic allograft valve. This strategy appears to have been successful in preventing persistent endocarditis and valve dehiscence in a limited number of patients.

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Section: Commentsmentioning

confidence: 99%