Non-traumatic childhood coma in Ebonyi State University Teaching Hospital, Abakaliki, South Eastern Nigeria

Ibekwe, RC; Ibekwe, MU; Onwe, OE; Nnebe-Agumadu, UH; Ibe, BC

doi:10.4103/1119-3077.79239

Cited by 26 publications

(28 citation statements)

References 8 publications

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“…Female predominance was seen in study by Ibekwe et [1,3,4,10]. It is also supported by other studies wherein infection of CNS was found to be leading cause of non-traumatic coma [8,9,11,12].…”

Section: Discussionsupporting

confidence: 77%

Study of clinical profile, etiology and immediate outcome in Non-traumatic coma in children

Shah¹,

Sanjeevani²,

Ronak³

et al. 2016

SJAMS

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Etiology of coma and clinical status at the time of presentation are likely predictors of outcome in cases of non-traumatic coma. The present study included of clinical profile, etiology of non-traumatic coma and immediate outcome in terms of survival and death in pediatric patients. This was prospective hospital based cohort study undertaken over a period of one year. A detailed history of all patients were taken and entered in case proforma. A complete clinical examination of patients was done. The etiology of coma was determined and the diagnosis of tuberculous meningitis was done. The data was analyzed using statistical software SPSS version 16. The clinical data was analyzed for the etiology of non-traumatic coma. Thirty one children survived and 19 died with mortality rate of 38%. Among survivors 20 (64%) were normal, 11(36%) had some disability (23%) mild disability, 10% moderately and 3% severely disabled. From the study, we got infections as the important cause of non-traumatic coma.

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Section: Discussionsupporting

confidence: 77%

Study of clinical profile, etiology and immediate outcome in Non-traumatic coma in children

Shah¹,

Sanjeevani²,

Ronak³

et al. 2016

SJAMS

View full text Add to dashboard Cite

show abstract

“…A study from Iran [8] also reported mortality of 16.6% and sequela of 28.66%. However, a study from Nigeria [9] reported higher mortality of 32.5%. This difference in mortality can be explained by the difference in aetiology, and diagnostic and treatment facilities.…”

Section: Discussionmentioning

confidence: 99%

Acute Febrile Encephalopathy in Children and Predictors of Mortality

Bokade

Gulhane

Bagul

et al. 2014

JCDR

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“…The next common causes of coma were metabolic ones, poisoning, and epilepsy (16). In a retrospective study in Nigeria, the most common causes of non-traumatic coma in 40 children were infectious ones, mostly by cerebral malaria (17). In another study, the most common causes of non-traumatic coma in 100 children were metabolic ones, followed by central nervous system infections and cerebral hemorrhage.…”

Section: Discussionmentioning

confidence: 99%

Non-traumatic Coma in Children in South-East of Iran

2014

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Background: Non-traumatic coma is a common condition in children that may cause considerable morbidity and mortality. Determining the most common causes of loss of consciousness in any specific region, and any sex and age group will dramatically reduce mortality and morbidity. Objectives: The purpose of this study was to evaluate the most common causes of non-traumatic coma among children in south east of Iran. Patients and Methods: All children (aged 1 month to 15 years) hospitalized for non-traumatic coma were included in this study. All of the patients received clinical measures such as history, physical, and neurological examinations. Glasgow coma scale (GCS) was used to determine the level of consciousness and paraclinical examinations, including CBC with differential, blood biochemistry, urine analysis, and liver function tests were performed on all patients. In case of indication, blood and urine culture, brain CT (Computed Tomography) scan or brain MRI (Magnetic Resonance Imaging), lumbar puncture, metabolic study, EEG (electroencephalogram), and so forth were carried out. Finally, the data were analyzed and the most common causes of loss of consciousness were determined. Results: Among the 123 children under investigation, 76 cases were male (61.8%) and 47 females (38.2%) with the mean age of 3.2 ± 0.64 years. The most common causes of loss of consciousness among children were as follows: toxic causes in 61 patients (49.6%), infectious causes in 30 patients (24.4%), metabolic causes in 11 patients (8.9%), structural brain abnormalities in 4 patients (3.3%) and seizure in 7 children (5.7%). Moreover, 10 patients (8.1%) had other causes of loss of consciousness. Conclusions: Toxic causes with an incidence of 49.6% were the most common cause of loss of consciousness among all age groups.

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Non-traumatic childhood coma in Ebonyi State University Teaching Hospital, Abakaliki, South Eastern Nigeria

Abstract: Infections were the predominant causes of non-traumatic coma in EBSUTH. In view of the high mortality among this group of patients, efforts at the control of malaria and other infections would significantly reduce the incidence of non-traumatic coma in this study site.

Cited by 26 publications

References 8 publications

Study of clinical profile, etiology and immediate outcome in Non-traumatic coma in children

Study of clinical profile, etiology and immediate outcome in Non-traumatic coma in children

Acute Febrile Encephalopathy in Children and Predictors of Mortality

Non-traumatic Coma in Children in South-East of Iran

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