2022
DOI: 10.1016/j.amjmed.2021.08.026
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Non-Vitamin K Antagonists Versus Warfarin in Patients with Atrial Fibrillation and Bioprosthetic Valves: A Systematic Review and Meta-Analysis

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Cited by 11 publications
(6 citation statements)
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“…The Rivaroxaban for Valvular Heart Disease and Atrial Fibrillation (RIVER) study suggested that rivaroxaban was non-inferior to warfarin in AF patients with bioprosthetic mitral valves. [138] A meta-analysis based on RCTs also demonstrated that the use of NOACs, compared to warfarin, significantly reduced the risk of stroke, systemic embolism, and major bleeding in patients with AF and bioprosthetic valves or prior valve repair. [139] The Edoxaban vs. Standard of Care and Their Effects on Clinical Outcomes in Patients Having Undergone Transcatheter Aortic Valve Implantation-AF (ENVISAGE-TAVI AF) study demonstrated that when used in AF patients undergoing successful transcatheter aortic valve replacement (TAVR), edoxaban was non-inferior to warfarin in reducing the risk of a postoperative major adverse cardiovascu-…”
Section: Patients With Af and Valvular Heart Diseasementioning
confidence: 99%
“…The Rivaroxaban for Valvular Heart Disease and Atrial Fibrillation (RIVER) study suggested that rivaroxaban was non-inferior to warfarin in AF patients with bioprosthetic mitral valves. [138] A meta-analysis based on RCTs also demonstrated that the use of NOACs, compared to warfarin, significantly reduced the risk of stroke, systemic embolism, and major bleeding in patients with AF and bioprosthetic valves or prior valve repair. [139] The Edoxaban vs. Standard of Care and Their Effects on Clinical Outcomes in Patients Having Undergone Transcatheter Aortic Valve Implantation-AF (ENVISAGE-TAVI AF) study demonstrated that when used in AF patients undergoing successful transcatheter aortic valve replacement (TAVR), edoxaban was non-inferior to warfarin in reducing the risk of a postoperative major adverse cardiovascu-…”
Section: Patients With Af and Valvular Heart Diseasementioning
confidence: 99%
“…138 A metaanalysis based on RCTs also demonstrated that the use of NOACs, compared to warfarin, significantly reduced the risk of stroke, systemic embolism, and major bleeding in patients with AF and bioprosthetic valves or prior valve repair. 139 The Edoxaban versus Standard of Care and Their Effects on Clinical…”
Section: Level Of Evidencementioning
confidence: 99%
“…The Rivaroxaban for Valvular Heart Disease and Atrial Fibrillation (RIVER) study suggested that rivaroxaban was noninferior to warfarin in AF patients with bioprosthetic mitral valves 138 . A meta‐analysis based on RCTs also demonstrated that the use of NOACs, compared to warfarin, significantly reduced the risk of stroke, systemic embolism, and major bleeding in patients with AF and bioprosthetic valves or prior valve repair 139 …”
Section: Stroke Preventionmentioning
confidence: 99%
“…[138] A meta-analysis based on RCTs also demonstrated that the use of NOACs, compared to warfarin, significantly reduced the risk of stroke, systemic embolism, and major bleeding in patients with AF and bioprosthetic valves or prior valve repair. [139] The Edoxaban vs. Standard of Care and Their Effects on Clinical Outcomes in Patients Having Undergone Transcatheter Aortic Valve Implantation-AF (ENVISAGE-TAVI AF) study demonstrated that when used in AF patients undergoing successful transcatheter aortic valve replacement (TAVR), edoxaban was non-inferior to warfarin in reducing the risk of a postoperative major adverse cardiovascular events. However, the incidence of major bleeding was higher with edoxaban than with vitamin K antagonist.…”
Section: Recommendations Recommendation Grade Level Of Evidencementioning
confidence: 99%