Non-volatile constituents from Monimiaceae, Siparunaceae and Atherospermataceae plant species and their bioactivities: An up-date covering 2000–2021

Mahdi, Ouafâa El; Ouakil, Abdelmoughite; Lachkar, Mohammed

doi:10.1016/j.phytochem.2022.113291

Cited by 5 publications

(5 citation statements)

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“…Plants from this family are usually shrubs or trees bearing essential oils. This plant family is rich in diverse metabolites, which are bioactive, including flavonoids, terpenoids, homogensitic acid derivatives and alkaloids [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…One such endemic plant T. peltata , belonging to the Monimiaceae family, has been evaluated regarding its antibacterial and antifungal properties against Escherichia coli (ATCC 25922), Staphylococcus aureus (ATCC 29213), Enterococcus faecalis (ATCC 21212), Pseudomonas aeruginosa (ATCC 27853), Aspergillus niger (ATCC 16404) and Candida albicans (ATCC 26219) only, leaving its phytochemical composition and other pharmacological properties unexplored [ 2 ]. Species from the Monimiaceae plant family are renowned for their uses in traditional medicine systems and known to be good sources of secondary metabolites bearing noticeable biological and therapeutic properties, mostly recognized for potential antioxidant and anticancer propensities [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

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Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

et al. 2023

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This study documents for the first time the phytochemical composition and biological activities of Tambourissa peltata Baker, an endemic plant from Mauritius. Phytochemical extraction was performed using ethyl acetate, methanol and distilled water as solvents. The phytochemical composition was determined through HPLC-MS and other standard assays. The DPPH, ABTS, FRAP, CUPRAC and phosphomolybdenum assays were employed for the determination of the antioxidant potential, whereas cell viability assays were used to determine the cytotoxicity. The highest phenolic and phenolic acid contents were obtained in the aqueous extract (179.91 ± 0.67 gallic acid equivalents/g and 55.74 ± 1.43 caffeic acid equivalents/g). The highest quantity of flavonoids was obtained in the ethyl acetate extract (28.97 ± 0.46 rutin equivalents/g). The methanolic extract was the highest source of flavonols (33.71 ± 0.13 mg catechin equivalents/g). A total of 34 phytochemicals were identified, mainly proanthocyanidins and flavonoid glycosides. The highest antioxidant activity in DPPH (973.40 ± 5.65 mg TE (Trolox equivalents)/g), ABTS (2030.37 ± 40.83 mg TE/g), FRAP (1461.39 ± 5.95 mg TE/g), CUPRAC (1940.99 ± 20.95 mg TE/g) and phosphomolybdenum (8.37 ± 0.23 mmol TE/g) assays was recorded for the aqueous extract. The ethyl acetate extract was the most active metal chelator. The highest acetylcholinesterase inhibitor was the methanolic extract, whereas the ethyl acetate extract was the most active against BChE. The tyrosinase enzyme was most inhibited by the methanolic extract. Alpha-amylase and glucosidase were most inhibited by the aqueous extract. The methanolic extract was capable of inducing cell cytotoxicity to the human colorectal carcinoma without damaging normal cells. T. peltata warrants further attention from the scientific community given its multifaceted biological properties.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

et al. 2023

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“…[40] The current study is the first to report the antimalarial activity of this species whose selection was based on taxonomic approach, since several antiplasmodial alkaloids are reported for Siparuna species, such as coclaurine and reticuline. [24,41,42,43] Complex LC-HRMS phytochemical profile was herein observed for S. krukovii ethanol extract what could hindering its standardization process, which is a fundamental step in medicinal plant validation processes.…”

Section: Discussionmentioning

confidence: 90%

In Vitroandin VivoAntimalarial Activity, Cytotoxicity and Phytochemical HRMS²Profile of Plants from the Western Pará State, Brazilian Amazonia

Viana dos Santos,

Costa Gontijo,

Alves do Nascimento

et al. 2023

Chemistry & Biodiversity

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Ethnopharmacology and botanical taxonomy are valid criteria used to selecting plants for antimalarial bioprospection purposes. Based on these two criteria, ethanol extracts of 11 plants from Santarém City vicinities, Western Pará State, Brazilian Amazonia, had their in vitro antiplasmodial activity against chloroquine‐resistant Plasmodium falciparum (W2 clone) assessed by the PfLDH method, whereas their cytotoxicity to HepG2‐A16 cells was assessed through MTT assay. Acmella oleracea, Siparuna krukovii and Trema micrantha extracts disclosed the highest rate of parasite growth inhibition (90 %) in screening tests. In vivo antimalarial assays were conducted with these extracts against Plasmodium berghei (NK 65 strain) infected mice. Inhibition rate of parasite multiplication ranged from 41.4 % to 60.9 % at the lowest extract dose (25 mg/kg). HPLC‐ESI‐HRMS2 analyses allowed the putative identification of alkylamides, fatty acids, flavonoid glycosides and alkaloids in ethanol extracts deriving from these three plant species. Results pointed towards A. oleracea flowers ethanol extract as the most promising potential candidate to preclinical studies aiming the development of antimalarial phytomedicine.

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“…El género Siparuna pertenece a la familia Siparunaceae (del orden Laurales). Esta familia se conoce desde la antigüedad por sus usos en la medicina tradicional y es una fuente rica de moléculas con potencial terapéutico emergente (El Mahdi et al, 2022). Se ha demostrado que los extractos crudos y los AEs de las Siparunáceas tienen propiedades biológicas notorias sobre microorganismos, en especial contra las bacterias.…”

Section: Estos Extractos Han Sido Ampliamente Estudiadosunclassified

Repellent and insecticidal activity of four essential oils from plants recolleted in Chocó-Colombia against Tribolium castaneum

Pino-Benitez,

Torralbo-Cabrera,

Stashenko

2024

BLACPMA

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This study aimed to determine the repellent and insecticidal activity of four essential oils (EOs) from plants collected in the Chocó rain forest, Colombia, against T. castaneum. Conventional hydrodistillation was used to obtain the EOs. The repellent and insecticidal activities were evaluated by the preference area and gas dispersion methods, respectively. Statistical differences (p<0.05) were determined by applying a student’s t-test. EOs of Siparuna guianensis, S. conica, Piper marginatum, and Nectandra acutifoliashowed excellent repellent properties as the main findings, highlighting S. conicaEO with 84% repellency (1μL/cm2), while P. marginatumshowed to be bioactive to the dose of 500 μL/mL (72 h), inducing mortality of 100% of the exposed population. In conclusion, the results evidenced the repellent properties of the EOs evaluated against T. castaneum, which allows us to conclude that these plant species are potential natural sources producing bio-repellents that contribute to the integrated control of T. castaneum.

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Non-volatile constituents from Monimiaceae, Siparunaceae and Atherospermataceae plant species and their bioactivities: An up-date covering 2000–2021

Cited by 5 publications

References 160 publications

Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

In Vitroandin VivoAntimalarial Activity, Cytotoxicity and Phytochemical HRMS²Profile of Plants from the Western Pará State, Brazilian Amazonia

Repellent and insecticidal activity of four essential oils from plants recolleted in Chocó-Colombia against Tribolium castaneum

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Non-volatile constituents from Monimiaceae, Siparunaceae and Atherospermataceae plant species and their bioactivities: An up-date covering 2000–2021

Cited by 5 publications

References 160 publications

Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

Unveiling the Antioxidant, Clinical Enzyme Inhibitory Properties and Cytotoxic Potential of Tambourissa peltata Baker—An Understudied Endemic Plant

In Vitroandin VivoAntimalarial Activity, Cytotoxicity and Phytochemical HRMS2Profile of Plants from the Western Pará State, Brazilian Amazonia

Repellent and insecticidal activity of four essential oils from plants recolleted in Chocó-Colombia against Tribolium castaneum

Contact Info

Product

Resources

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In Vitroandin VivoAntimalarial Activity, Cytotoxicity and Phytochemical HRMS²Profile of Plants from the Western Pará State, Brazilian Amazonia