Nonanesthesiologist-administered propofol sedation for colonoscopy is safe and effective

Abstract

Colonoscopy under endoscopist-controlled propofol sedation in low-risk patients is safe and effective, allowing for a complete exploration, although patients at least 65 years old and/or classified as ASA II are more likely to present a decrease in blood pressure and have a prolonged recovery time.

Safety analysis of endoscopist‐directed propofol sedation: A prospective, national multicenter study of 24 441 patients in German outpatient practices

“…4,6 Several reports worldwide stated that EDP is a safe procedure. 15,19,20,[22][23][24][25][26][27][28][29] Nevertheless, some National Societies of Anaesthesiology have officially and publicly dissociated themselves from the NAAP guidelines, 16 and the Centers for Medicare and Medicaid Services have issued a clarification statement of an interpretive guideline that shut down the practice of EDP sedation in most hospitals in the United States. 18 These policies were pursued without any supporting evidence.…”

Propofol administration is safe in adult eosinophilic esophagitis patients sensitized to egg, soy, or peanut

“…Propofol was administered as the sole sedative agent under the supervision of two senior gastroenterologists (JMI and AJL), with expertise on nonanesthesiologist propofol administration . An initial bolus of 20–40 mg of propofol (Generic product 10 mg/ml, Fresenius Kabi, Bad Homburg, Germany) was administered intravenously in all patients.…”

A clinical trial comparing propofol versus propofol plus midazolam in diagnostic endoscopy of patients with a low anesthetic risk

“…Despite the extensive use of propofol, caution should be taken when administrated by non-anesthetists as there is no antagonist and there is also a potential to induce general anesthesia. Although, its safety in the hands of trained endoscopists has been demonstrated in numerous studies (5)(6)(7)(8)(9)(10)(11)(12).…”