Nonbacterial Thrombotic Endocarditis

Liu, Joshua; Frishman, William H.

doi:10.1097/crd.0000000000000106

Cited by 97 publications

(97 citation statements)

References 40 publications

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“…It was formerly known as marantic endocarditis as it was often encountered in critically unwell patients, or at autopsy. 1 NBTE is rare and shows no sex predilection. It is primarily associated with cancer, usually adenocarcinoma.…”

Section: Discussionmentioning

confidence: 99%

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Image of the month: Rapidly evolving mitral stenosis: an unusual case of endocarditis

McBriar¹,

Kearney²,

Cole³

2020

Clinical Medicine

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Section: Discussionmentioning

confidence: 99%

“…It has also been described in association with rheumatoid arthritis, sepsis and burns. 1 Pulmonary and cerebral emboli are the primary presenting features of NBTE, as well as embolisation of the spleen, kidney and skin. 2 Presentation with valvular dysfunction, as described here, is less common.…”

Section: Discussionmentioning

confidence: 99%

Image of the month: Rapidly evolving mitral stenosis: an unusual case of endocarditis

McBriar¹,

Kearney²,

Cole³

2020

Clinical Medicine

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“…These vegetations consist of fibrin mixed with immune complexes and platelets [1]. Endothelial damage in the setting of a hypercoagulable state is thought to be a precipitating factor in NBTE [13]. NBTE is commonly associated with malignancy and SLE.…”

Section: Discussionmentioning

confidence: 99%

Lupus-Negative Libman-Sacks Endocarditis Complicated by Catastrophic Antiphospholipid Syndrome

et al. 2017

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Libman-Sacks endocarditis is characterized by sterile and verrucous lesions that predominantly affect the aortic and mitral valves. In most cases, patients do not have significant valvular dysfunction. However, patients with significant valvular dysfunction may present with serious complications such as cardiac failure, arrhythmias, and thromboembolic events. Recently, association of Libman-Sacks endocarditis with antiphospholipid antibody syndrome (APS) has been made. APS is most commonly defined by venous and arterial thrombosis, recurrent pregnancy loss, and thrombocytopenia. While the syndrome can be a primary syndrome, it is usually secondary to systemic lupus erythematosus. Catastrophic antiphospholipid syndrome (CAPS) can be a life-threatening presentation of APS and can occur in 1% of patients with antiphospholipid syndrome. We present a very rare case of a young female patient with lupus-negative Libman-Sacks endocarditis complicated by CAPS.

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“…Many of these patients have had multiple previous surgical procedures involving prosthetic material and are, in general, living longer-both are risk factors for developing endocarditis [14,15]. In addition, while the overall focus tends to be on infectious causes, there is clearly much to learn about noninfectious causes of endocarditis such as marantic or Libman-Sacks endocarditis [16].…”

Section: Microbiologymentioning

confidence: 99%

Introductory Chapter: Introduction to Advanced Concepts in Endocarditis

Firstenberg¹

2018

Advanced Concepts in Endocarditis

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Nonbacterial Thrombotic Endocarditis

Cited by 97 publications

References 40 publications

Image of the month: Rapidly evolving mitral stenosis: an unusual case of endocarditis

Image of the month: Rapidly evolving mitral stenosis: an unusual case of endocarditis

Lupus-Negative Libman-Sacks Endocarditis Complicated by Catastrophic Antiphospholipid Syndrome

Introductory Chapter: Introduction to Advanced Concepts in Endocarditis

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