Noncompliance in hospitalized patients with AIDS

Blumenfield, Michael; Milazzo, Jane; Wormser, Gary P.

doi:10.1016/0163-8343(90)90075-n

Cited by 19 publications

(5 citation statements)

References 7 publications

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“…Psychological issues have also received some attention, and depression 25,27 and hopelessness 11,27 have been associated with non-adherence. Several authors have highlighted that the patients' views and beliefs about their illness and the effectiveness of medication are predictors of adherence 10,12,26 .…”

Section: Introductionmentioning

confidence: 99%

Factors associated with adherence to antiretroviral medication in HIV-infected patients

et al. 2002

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The aim of the study was to assess adherence with antiretroviral medication in a sample of HIV patients in Hong Kong and identify predictors of adherence. The study used a cross-sectional correlational design. Adherence behaviour was assessed with the use of self-reports. Other scales assessed knowledge with HIV medication, coping, health locus of control, anxiety, depression and fatigue. A blood sample was also obtained to assess CD4+ counts and viral load. Sociodemographic characteristics and medical information were obtained from the medical records. A high adherence rate was found in this sample of 136 predominantly Chinese patients. There were only 13.7% of the patients being classified as non-adherent. Predictors of adherence included high self-efficacy in terms of being certain that the medication schedule will be followed all or most of the time as directed, low tension-anxiety scores, and low intensity of nausea and vomiting (R2=0.304). An expanded regression model revealed additional factors influencing adherence, including coping variables, pain and numbness in the hands and feet, age, disease stage, internal locus of control, fatigue, family support and taking medication twice daily. This model explained 49% of the variance in adherence. The results suggest that adherence is a multidimensional concept. Every effort should be made to assess in individuals those variables found to affect adherence and alter them whenever possible. Continuous support of patients and individualized medication programmes that will help patients adjust their treatment to their lifestyle are recommended.

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Section: Introductionmentioning

confidence: 99%

Factors associated with adherence to antiretroviral medication in HIV-infected patients

et al. 2002

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“…Research has shown lower rates of HAART adherence among those with a mood or anxiety disorder (Paterson et al, 2000;Tucker et al, 2003), and depression has been strongly associated with nonadherence among diverse samples of those living with HIV Catz, Kelly, Bogart, Benotsch, & McAuliffe, 2000;Gonzalez et al, 2004;Mellins et al, 2002;Murphy et al, 2005). Depression among HIV-positive persons can result in nonadherence as patients 'give up' and may even refuse treatment altogether (Blumenfield, Milazzo, & Wormser, 1990). Depressed individuals also tend to be less motivated to take their HIV medications (Lyketsos et al, 1996), may have impaired cognitive functioning that makes it difficult to remember to follow through with treatment recommendations or may have a pessimistic outlook about the effectiveness of treatment (DiMatteo, Lepper, & Croghan, 2000).…”

Section: Affective Factorsmentioning

confidence: 99%

Patient-related Factors Predicting HIV Medication Adherence among Men and Women with Alcohol Problems

2007

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The study explored the relationship between HIV medication adherence and alcohol, cognitive, social and affective factors in 272 persons with alcohol problems. Alcohol and cognitive factors significantly differentiated those who did and did not adhere. Specifically, adherence confidence and number of drinks emerged as subfactors driving the associations to adherence. Among those who were less than perfectly adherent (n = 154), only alcohol factors predicted levels of nonadherence. Cognitive factors play a role in understanding some of the differences between those who do and do not adhere to their HIV medications, but they do not differentiate among levels of nonadherence.

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“…Compliance with HIV treatment has been and continues to be studied extensively (Blumenfield, Milazzo & Wormser, 1990; Catz, Mc Clure, Jones & Brantley, 1999; Chaisson et al, 1996; Chesney, 1997; Chesney et al, 1999; Cramer, 1991; Cramer & Spilker, 1991; Ickovics & Meisler, 1997; Krasnegor, Epstein, Johnson, & Yaffe, 1993; Lazzarini et al, 1999; Singh, Squier, Sivek, Wagener, Hong Nguyen, & Yu, 1996; Wagner & Rabkin, 2000). Following the introduction of tritherapy, its importance and implications have changed.…”

Section: Compliance: Approaches and Characteristicsmentioning

confidence: 99%

Therapeutic compliance methodologies in HIV-infection treatment: A comparative study

Tarquinio¹,

Fischer²

2001

Swiss Journal of Psychology

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Compliance with HIV treatment has been studied extensively. Following the introduction of tritherapy, its importance and implications have changed. Antiretroviral treatments entail taking up to 20 pills a day at set hours, for which there are often numerous undesirable and even toxic side effects. These therapeutic constraints lead to what is labeled greater or lesser compliance. Certain factors such as side effects, modes of contamination, and trust in physicians appear to be more closely linked to noncompliance than others. A recurring problem is how to assess this compliance. There are two types of measures that serve this purpose: direct (biological) or indirect (interviews, questionnaires). It is often very difficult to know how authors actually proceed in assessing their patients' compliance. To determine this, we analyzed 27 of the 310 studies published between 1990 and 2000 on therapeutic compliance in HIV-infected patients. These 27 studies were not chosen because they are a statistically representative sample of the related literature, but because they account quite well for the different types of methods used to measure compliance with HIV treatment. Our analysis shows that compliance measures are quite diverse and can be either a combination of direct and indirect measures, or consist of one or more direct measures or only indirect measures. These three methodological orientations are discussed first. The limits and biases of self- and hetero-compliance assessment, so often neglected, are studied next. Finally, problems related to the temporal facet of compliance behavior are analyzed, namely definition of the concept, need for a more precise theoretical elaboration, and the place of health psychology in relation to the medical sciences.

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Noncompliance in hospitalized patients with AIDS

Cited by 19 publications

References 7 publications

Factors associated with adherence to antiretroviral medication in HIV-infected patients

Factors associated with adherence to antiretroviral medication in HIV-infected patients

Patient-related Factors Predicting HIV Medication Adherence among Men and Women with Alcohol Problems

Therapeutic compliance methodologies in HIV-infection treatment: A comparative study

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