Red palm weevil (RPW) causes severe damage to date palm trees, leading to the death of trees if not detected and treated in time. A major obstacle in RPW control is the difficulty in identifying an early stage infestation In the present study, we measured the efficacy of some non-invasive optical devices including cameras (digital camera and thermal camera), TreeRadarUnit™ (TRU) (Radar 2000, Radar 900), resistograph, magnetic DNA biosensor, and Near-infrared Spectroscopy (NIRS) to detect RPW infestation in date palm trees under field conditions at Riyadh, Saudi Arabia. Date palm trees used in these experiments were selected based on visual observations. After inspection of date palm trees with different devices to detect RPW infestation, each tree was taken down and dissected in detail to validate the accuracy of each device. Results indicated that the visual RPW detection approach presented the highest accuracy (87%) followed by Radar 2000 (77%), Radar 900 (73%), resistograph (73%), thermal camera (61%), and digital camera (52%).Moreover, different stages of RPW placed in plastic cups were fastened onto the healthy date palm trunks to judge RPW presence, the magnetic DNA biosensor correctly detected RPW eggs 75% of the time, followed by detection of larvae (64%) and the control (empty cup) (54%). In another experiment where determinations were made in an open area, the efficiency of the DNA biosensor for detecting adults was 100%, followed by 83%, 63%, 60%, and 39% for pupae, larvae, eggs, and control, respectively. Absorption spectra generated through NIRS for infested, wounded, and control samples of date palm tissue showed a remarkable variation in the gradient of the corresponding peaks between 1850 nm and 1950 nm. Based on the detection efficiency of the tested devices, the resistograph and NIRS have the best potential to detect RPW infestation in date palm trees.