Nondiabetic thigh muscle infarction presenting as a possible primary antiphospholipid syndrome

Nishikai, Masahiko; Ichihara, Nao; Bito, Seiji; Akiya, Kumiko

doi:10.1007/s10165-003-0239-4

Cited by 1 publication

(3 citation statements)

References 7 publications

(7 reference statements)

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“…123 MRI was used for diagnosis, and the patient was managed with bed rest and analgesic treatment. 123 In 2003, Nishikai et al reported a non-diabetic patient with no coagulation abnormalities, 17 but with positive aCL and history of cerebral infarction, who was diagnosed with thigh muscle infarction. Biopsy confirmed the diagnosis, and other differential diagnoses were ruled out.…”

Section: Muscle Infarctionmentioning

confidence: 99%

“…The patient was diagnosed with possible APS as well. 17 The significance of aPL in the pathogenesis of muscle infarction is not established yet. This could be explained by two main factors: (1) the rarity of the condition and (2) the associated risk factors, most notably diabetic microvascular disease.…”

Section: Muscle Infarctionmentioning

confidence: 99%

“…Table 1 lists the reported musculoskeletal complications and Table 2 summarizes studies reporting these complications in APS patients. 4–28 The aim of the current review is to highlight the involvement of APS in the musculoskeletal system and suggest a management plan for the associated complications.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Musculoskeletal manifestations of the antiphospholipid syndrome

Noureldine

Khamashta

Merashli

et al. 2016

Lupus

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The scope of clinical and laboratory manifestations of the antiphospholipid syndrome (APS) has increased dramatically since its discovery in 1983, where any organ system can be involved. Musculoskeletal complications are consistently reported in APS patients, not only causing morbidity and mortality, but also affecting their quality of life. We reviewed all English papers on APS involvement in the musculoskeletal system using Google Scholar and Pubmed; all reports are summarized in a table in this review. The spectrum of manifestations includes arthralgia/arthritis, avascular necrosis of bone, bone marrow necrosis, complex regional pain syndrome type-1, muscle infarction, non-traumatic fractures, and osteoporosis. Some of these manifestations were reported in good quality studies, some of which showed an association between aPL-positivity and the occurrence of these manifestations, while others were merely described in case reports.

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Section: Muscle Infarctionmentioning

confidence: 99%

Section: Muscle Infarctionmentioning

confidence: 99%