Nondrug Interventions for Treatment of Hypertension

Woolf, Kevin J.; Bisognano, John D.

doi:10.1111/j.1751-7176.2011.00524.x

Cited by 21 publications

(14 citation statements)

References 79 publications

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“…157,158 Numerous additional approaches and complementary therapies have also been described. 16,159 These treatments are outlined in the online-only Data Supplement-Methods and Results. However, they were not systematically reviewed, and official CORs are not provided in this scientific statement because of the paucity of high-quality clinical trials, because of the investigational nature of the procedures, because they were considered a dietary approach (eg, nutraceuticals), or because the method pertains only to a selected set of individuals (eg, continuous positive airway pressure).…”

Section: Additional Alternative Approachesmentioning

confidence: 99%

“…9,15,16 For the purposes of this scientific statement, these therapies are called alternative approaches and are broadly classified into 3 categories: behavioral therapies, noninvasive procedures or devices, and exercise-based regimens. There are several reasons why these strategies are likely to become increasingly important and commonly used tools in the management of high BP.…”

Section: Aims and Rationalementioning

confidence: 99%

“…Obstructive sleep apnea (OSA) has been identified as a risk factor for hypertension in many [13][14][15] but not all studies 16 . Excess adiposity is a strong risk factor for both hypertension and OSA and could serve as the underlying intermediate mechanism explaining the association between these comorbidities.…”

Section: Continuous Positive Airway Pressure (Cpap)mentioning

confidence: 99%

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Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure

Brook¹,

Appel²,

Rubenfire³

et al. 2013

Hypertension

Self Cite

490

310

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Abstract-Many antihypertensive medications and lifestyle changes are proven to reduce blood pressure. Over the past few decades, numerous additional modalities have been evaluated in regard to their potential blood pressure-lowering abilities. However, these nondietary, nondrug treatments, collectively called alternative approaches, have generally undergone fewer and less rigorous trials. This American Heart Association scientific statement aims to summarize the blood pressure-lowering efficacy of several alternative approaches and to provide a class of recommendation for their implementation in clinical practice based on the available level of evidence from the published literature. The American Heart Association makes every effort to avoid any actual or potential conflicts of interest that may arise as a result of an outside relationship or a personal, professional, or business interest of a member of the writing panel. Specifically, all members of the writing group are required to complete and submit a Disclosure Questionnaire showing all such relationships that might be perceived as real or potential conflicts of interest. Expert peer review of AHA Scientific Statements is conducted by the AHA Office of Science Operations. For more on AHA statements and guidelines development, visit http://my.americanheart.org/statements and select the "Policies and Development" link.

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Section: Additional Alternative Approachesmentioning

confidence: 99%

Section: Aims and Rationalementioning

confidence: 99%

Section: Continuous Positive Airway Pressure (Cpap)mentioning

confidence: 99%

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Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure

Brook¹,

Appel²,

Rubenfire³

et al. 2013

Hypertension

Self Cite

490

310

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“…Non-pharmacological interventions, including weight loss, reduced sodium intake, regular physical activity, smoking cessation, and the moderation of alcohol intake, are recommended [2,3]. Antihypertensive drugs, including angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), beta-blockers, calcium channel blockers (CCBs), and thiazide-type diuretics, are commonly used [2].…”

Section: Introductionmentioning

confidence: 99%

Auricular acupuncture for prehypertension and stage 1 hypertension: study protocol for a pilot multicentre randomised controlled trial

Kim

Jung

Lee

et al. 2013

Trials

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BackgroundHypertension, a worldwide public health problem, is a major risk factor for cardiovascular and kidney disease, and the medical and economic burden of hypertension is increasing. Auricular acupuncture has been used to treat various diseases, including hypertension. Several studies have shown that auricular acupuncture treatment decreases blood pressure in patients with hypertension; however, the scientific evidence is still insufficient. Therefore, we aimed to perform a randomised controlled clinical trial in patients with prehypertension and stage 1 hypertension to evaluate the effect and safety of auricular acupuncture.Methods/designsThis on-going study is a two parallel arm, assessor-blinded, randomised controlled trial. Sixty participants with prehypertension and stage 1 hypertension will be recruited and randomly allocated into two groups in a 1:1 ratio. Participants in the auricular acupuncture group will receive auricular acupuncture treatment two times per week for 4 weeks. Participants in the usual care group will not receive any acupuncture treatment during the study period. All participants in both groups will be provided with verbal and written educational materials regarding the dietary and physical activity habits for controlling high blood pressure, and they will self-manage their lifestyle, including diet and exercise, during the study. The primary outcome is the 24-h average systolic and diastolic blood pressure, as measured with an ambulatory monitor. The secondary outcomes are the mean change in the average systolic and diastolic blood pressure during day- and night-time, the circadian rhythm of blood pressure, the mean arterial pressure, the change in blood pressure before and after auricular acupuncture treatment, the EuroQOL-5D (EQ-5D), heart rate variability (HRV), body mass index (BMI) and laboratory examination, including lipid profile and high sensitivity C-reactive protein (hs-CRP). Safety will be assessed at every visit.DiscussionThis pilot multicentre randomised controlled trial will explore the feasibility of further auricular acupuncture research and provide important clinical evidence for the effect and safety of auricular acupuncture on blood pressure in patients with prehypertension and stage 1 hypertension compared with usual care.Trial registrationClinical Research Information Service: KCT0000169

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“…Nondrug interventions are a valued component of any plan designed for the treatment of hypertension. Such interventions can be quite varied, as was nicely summarized by Woolf and Bisognano 1 in their inclusive article on this topic.In their paper, there is discussion on baroreflex stimulation and renal nerve denervation; however, these are not traditionally viewed as nondrug interventions and will not be further addressed in this commentary.…”

mentioning

confidence: 99%

Nondrug Interventions for the Treatment of Hypertension: Varying Effect

Sica

2011

J of Clinical Hypertension

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Nondrug Interventions for Treatment of Hypertension

Cited by 21 publications

References 79 publications

Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure

Beyond Medications and Diet: Alternative Approaches to Lowering Blood Pressure

Auricular acupuncture for prehypertension and stage 1 hypertension: study protocol for a pilot multicentre randomised controlled trial

Nondrug Interventions for the Treatment of Hypertension: Varying Effect

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