Nonenhanced hepatic cavernous hemangioma with multiple calcifications: CT and pathologic correlation

Mitsudo, Kazuaki; Watanabe, Yuji; Saga, Tsutomu; Dohke, Masako; Sato, Noriko; Minami, Kazuhiko; M, Shigeyasu

doi:10.1007/bf01213272

Cited by 30 publications

(8 citation statements)

References 5 publications

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“…Hepatic hemangiomas are the most common benign FLL, with an incidence of 2%‐20% 1‐5. Classic MRI features include round or lobular margins, marked T2 hyperintensity (referred to as light‐bulb bright), and characteristic enhancement pattern 26‐30. Three distinct patterns of enhancement have been described on ECA‐enhanced MRI, with reported specificities of 100% and diagnostic accuracies of 95% 31.…”

Section: Fll Characterizationmentioning

confidence: 99%

Magnetic resonance imaging of focal liver lesions: Approach to imaging diagnosis

2011

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This article is a review of magnetic resonance imaging (MRI) of incidental focal liver lesions. This review provides an overview of liver MRI protocol, diffusion-weighted imaging, and contrast agents. Additionally, the most commonly encountered benign and malignant lesions are discussed with emphasis on imaging appearance and the diagnostic performance of MRI based on a review of the literature. (HEPATOLOGY 2011;54:2227-2237 T he incidence of incidentally detected focal liver lesions (FLL) parallels growth in imaging utilization. The majority of FLL arising in noncirrhotic livers are benign. Hemangiomas, focal nodular hyperplasias (FNH), and adenomas (HCA) are the most commonly encountered solid benign lesions. 1-3The most commonly encountered malignant lesions in noncirrhotic livers are metastases. Hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (ICC) occur in the setting of chronic liver disease.Maximizing specificity and accuracy of cross-sectional imaging in the context of these incidental liver lesions is paramount in avoiding unnecessary biopsies, which may portend a postprocedural morbidity of 2.0% to 4.8% and mortality of 0.05%. [4][5][6] Ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) are the main liver imaging modalities. A meta-analysis comparing contrast-enhanced ultrasound, CT, and MRI in evaluating incidental FLLs demonstrated similar diagnostic performance with specificities ranging from 82%-89% and no significant difference in the summary receiver operating characteristic between modalities.7 Given the lack of ionizing radiation and relative nonavailability of ultrasound contrast in the U.S., MRI is the imaging test of choice for FLL characterization, demonstrating similar if not superior performance to CT. This review focuses on the diagnostic performance of MRI in evaluating the most common FLL in noncirrhotic livers with additional discussion of HCC and ICC, which, although highly associated with chronic liver disease, are important differential considerations. Liver MRIBasic Protocol. A comprehensive liver protocol evaluates the parenchyma, vasculature, and biliary system. This is accomplished by way of a combination of single-shot T2-weighted fast spin-echo, gradient echo T1-weighted in-and opposed-phase, fat suppressed T2-weighted, dynamic pre-and postcontrast T1-weighted imaging and potentially subtraction of prefrom postcontrast image sets.8 High-quality images require compromise between achievable resolution and the need for breath-holding, which limits each sequence to 20 seconds or less. Breath-holding is not always possible in sick patients. As a result, modifications to the basic protocol may include the addition of free-breathing sequences, respiratory-gating, motion correction techniques (i.e., BLADE or PROPELLER or radial acquisition of k-space).MRI quality can be variable due to differences in sequences, gradient, and magnetic field strength. In recognition of this variability, a recent publication on behalf

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Section: Fll Characterizationmentioning

confidence: 99%

Magnetic resonance imaging of focal liver lesions: Approach to imaging diagnosis

2011

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“…schistosomiasis, histoplasmosis, fascioliasis, echinococcosis) (Grange et al 1974, Monzawa et al 1993, Pan et al 1999, Polat & Atamanalp 2009), bacterial infections (e.g. tuberculosis) (Maglinte et al 1988, Wong & Ng 1993, Sheen-Chen et al 2001, viral infections (Konen et al 2000, Saikia et al 2007 or in diseases causing tissue necrosis such as neoplasia (Shapiro et al 1988, Mitsudo et al 1995, Nagakura et al 1999, Murakami et al 2013, Bayraktutan et al 2014, Wang et al 2014, Inoko et al 2015, granulomas (Akimoto et al 1993), haematomas or abscesses (Reeder 1975, Paley & Ros 1998, Stoupis et al 1998. One paper reports two cases of biliary wall calcification in humans in Langerhans cell histiocytosis (Caruso et al 2008), detected by CT.…”

Section: Introductionmentioning

confidence: 99%

Clinical relevance of radiographic linear branching mineral opacities in the canine liver

Genain

Barbosa

Herrtage

et al. 2017

J of Small Animal Practice

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“…A particular pattern that consists of multiple spots of calcifications corresponded to phleboliths. 9 To our knowledge, the hepatic haemangioma with both fluid-fluid levels and calcifications like our case has never been reported before.…”

Section: Discussionmentioning

confidence: 48%

Multiple hepatic hemangiomas with fluid‐fluid levels

Lee

Lim

Jeon

2007

Australasian Radiology

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Hepatic haemangiomas with fluid-fluid levels are known to be rare with only five cases reported in the English literature. According to the previous reports, the presence of fluid-fluid level could attribute to the separation of blood cells and serous fluid because of the extremely slow flow in cavernous haemangioma of the liver. We describe the imaging features of multiple hepatic haemangiomas with fluid-fluid levels, which was pathologically proven with ultrasonography guided biopsy.

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Nonenhanced hepatic cavernous hemangioma with multiple calcifications: CT and pathologic correlation

Cited by 30 publications

References 5 publications

Magnetic resonance imaging of focal liver lesions: Approach to imaging diagnosis

Magnetic resonance imaging of focal liver lesions: Approach to imaging diagnosis

Clinical relevance of radiographic linear branching mineral opacities in the canine liver

Multiple hepatic hemangiomas with fluid‐fluid levels

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