Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

Perzin, Karl H.; Pushparaj, Neela

doi:10.1002/1097-0142(197811)42:5<2399::aid-cncr2820420541>3.0.co;2-p

Cited by 92 publications

(35 citation statements)

References 20 publications

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“…They can occur solitary outside the bone marrow [solitary bone plasmacytomas (SBP), solitary extramedullary plasmacytomas (EMP)], but can also be associated with multiple myeloma (MM) [2][3][4]. EMPs account for 4% of all non-epithelial tumours of the upper respiratory tract [5]. They arise submucosally (80%), in particular at the nasopharynx, nose cavity, sinuses and tonsils.…”

Section: Introductionmentioning

confidence: 99%

Extramedullary plasmacytomas in the head and neck region

Straetmans

Stokroos

2008

Eur Arch Otorhinolaryngol

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Extramedullary plasmacytoma (EMP) arises outside the bone marrow, particularly in the head and neck region (nasopharynx, nose cavity, sinuses, and tonsils), and can be associated with multiple myeloma (MM). Three cases of EMP in the head and neck region are described: a Wrst case describes an EMP of the subglottis 3 years after treatment of MM, a second case of an EMP solitary in the middle ear presenting as a jugular foramen syndrome, and a third case of an EMP localised at the epiglottis, recurring at the Xoor of the nose cavity. Treatment of each EMP was surgical. We reviewed literature about aetiology, clinical course, diagnostics, treatment and prognosis. Important presenting symptoms vary from epistaxis, rhinorrhoea, a sore throat, dysphonia to haemoptoea. Association with MM must be conWrmed or excluded. Histopathological examination, with immunological staining or Xow cytometry conWrms the diagnosis. CT and MRI are useful in staging EMP. The treatment of EMP is surgery and/or radiotherapy. The prognosis depends on tumour size (>5 cm) and nodal involvement. The 10-year survival rate is 50-80%.

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Section: Introductionmentioning

confidence: 99%

Extramedullary plasmacytomas in the head and neck region

Straetmans

Stokroos

2008

Eur Arch Otorhinolaryngol

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“…Extramedullary plasmacytoma accounts for less than 1% of all head and neck cancers. 48 Occasionally, it presents as a solitary lesion in the nasal cavity. Extramedullary plasmacytoma tends to occur in the sixth and seventh decades of life, and it is three to four times more common in men than in women.…”

Section: Discussionmentioning

confidence: 99%

Should Voriconazole be the Primary Therapy for Chronic Invasive Sinus Aspergillosis (CISA)?

2011

An International Journal Clinical Rhinology

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Background: The endonasal endoscopic surgery has stood the test of time in managing inflammatory as well as other diseases affecting nose and paranasal sinuses.Objective: To report our experience with endonasal endoscopic surgery of benign tumors and tumor-like conditions of the nose and paranasal sinuses. Methods:The medical records of 92 patients with tumors and tumor-like conditions, who had undergone endoscopic surgery for removal of their lesions between 1999 and 2010, were retrospectively studied. Results:The study included a total of 92 patients. Out of these patients, there were 24 with inverted papilloma, six juvenile nasopharyngeal angiofibroma, 10 intranasal hemangioma,10 fibro-osseous lesions, four olfactory neuroblastoma, two each schwannoma and neurofibroma, one glioma, two plasmacytoma, two pleomorphic adenoma, 11 pyogenic granuloma, 14 mucoceles and four giant cell reparative granuloma. The patients had a follow-up ranging from 6 to 78 months (mean: 42). Follow-up assessment included endoscopy and yearly CT scans. Three cases of recurrent tumor-two inverted papilloma and one mucocele were noted. These were managed endoscopically. There were no major complication encountered in this study and minor complications were orbital fat protrusion 8, synechiae 6 cases.Conclusion: Benign tumors and tumor-like conditions of the nose and paranasal sinuses can be managed with endonasal endoscopic surgery with minimal morbidity.

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“…4,5 Extramedullary plasmacytomas represent less than 1% of all head and neck malignancies 6 and it accounts for 4% of all nonepithelial tumors of the nasal cavity, nasopharynx and paranasal sinuses. 7 We report a rare case of extramedullary plasmacytoma arising from the maxillary antrum.…”

Section: Introductionmentioning

confidence: 94%

Primary Extramedullary Plasmacytoma of Maxillary Sinus

Ray¹,

Mishra²,

Khatua³

et al. 2013

An International Journal Clinical Rhinology

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A rare case of extramedullary plasmacytoma of maxillary sinus in a 58-year-old man presenting with right-sided nasal obstruction and intermittent blood tinged nasal crusting. Nasal endoscopy revealed that a dark red colored mass arising from the lateral wall of nose. A biopsy specimen was diagnosed as plasmacytoma (Kappa light chain type). Serum and urine electrophoresis failed to detect any myeloma component or Bence-Jones protein. All other screening tests to rule out multiple myeloma were negative. These findings confirmed the diagnosis of extramedullary plasmacytoma. The mass was completely excised by lateral rhinotomy approach. No recurrence has been noted at the end of 6 months follow-up.

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Nonepithelial tumors of the nasal cavity, paranasal sinuses and nasopharynx. A clinicopathologic study. IX. Plasmacytomas

Cited by 92 publications

References 20 publications

Extramedullary plasmacytomas in the head and neck region

Extramedullary plasmacytomas in the head and neck region

Should Voriconazole be the Primary Therapy for Chronic Invasive Sinus Aspergillosis (CISA)?

Primary Extramedullary Plasmacytoma of Maxillary Sinus

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