In the present paper, we analyze the signatures of long-range persistence in seismic sequences along Circum-Pacific subduction zones, from Chile to Kermadec, extracted from the National Earthquake Information Center (NEIC) catalog. This region, known as the Pacific Ring of Fire, is the world's most active fault line, containing about 90% of the world's earthquakes. We used the classical rescaled range (R/S) analysis to estimate the long-term persistence signals derived from a scaling parameter called the Hurst exponent, H. We measured the referred exponent and obtained values of H > 0.5, indicating that a long-term memory effect exists. We found a possible fractal relationship between H and the b s (q)-index, which emerges from the non-extensive Gutenberg-Richter law as a function of the asperity. Therefore, H can be associated with a mechanism that controls the level of seismic activity. Finally, we concluded 1 arXiv:1912.02092v1 [physics.geo-ph] 3 Dec 2019Running title • November 2012 • Vol. XXI, No. 1 that the dynamics associated with fragment-asperity interactions can be classified as a self-affine fractal phenomenon.