Noninfectious transfusion-associated adverse events

Hong, Hong; Duque, Miriam Andrea; Mana, Abdulaziz F. Al; Wu, Yanyun

doi:10.21037/aob-21-83

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Advancements in immunosuppressive drugs have played a pivotal role in mitigating immune reactions against non-ABO antigens in the perspective of organ transplantation [23]. These drugs are designed to moderate the recipient's immune response, thus dropping the hazard of graft rejection and improving the long-term existence of transplanted organs.…”

Section: Advancements In Immunosuppressive Drugsmentioning

confidence: 99%

Understanding the Immunological Significance of Blood Groups in Organ Transplantation

Pushpa,

Shanmugha Priya,

S. Kumar

et al. 2024

Blood Groups - New Perspectives [Working Title]

View full text Add to dashboard Cite

This chapter investigates the relationship between blood groups and the immune system in the background of organ transplantation. It explores how blood group compatibility plays a serious role in determining the success of organ transplants and mitigating the risk of rejection. The chapter focuses on the underlying mechanisms that affect graft acceptance or rejection by looking at the immunological importance of blood types. It explores the complex interactions between antibodies, antigens, and the immune response and emphasizes how variations in blood type antigens may trigger the immunological reactions and affect the success of transplants. Furthermore, the clinical implications of blood group matching in organ transplantation are also highlighted in this chapter. It also discusses emerging advancements in immunogenetics and immunosuppressive therapies that aim to overcome the immunological challenges associated with blood group disparities. Overall. The chapter serves as a valuable resource for healthcare professionals and researchers to facilitate improved matching strategies and enhanced outcomes in the field of transplantation medicine.

show abstract

Section: Advancements In Immunosuppressive Drugsmentioning

confidence: 99%

Understanding the Immunological Significance of Blood Groups in Organ Transplantation

Pushpa,

Shanmugha Priya,

S. Kumar

et al. 2024

Blood Groups - New Perspectives [Working Title]

View full text Add to dashboard Cite

show abstract

Is it time for the death knell of single‐unit plasma?

Gammon,

Auron,

Tolich

et al. 2024

Vox Sanguinis

View full text Add to dashboard Cite

Background and ObjectivesA plasma transfusion dose should be weight‐based (10–20 mL/kg), which equates to three to four units in an average‐sized adult; therefore, the transfusion of single units under most circumstances is sub‐therapeutic.Materials and MethodsThis retrospective observational study examined the prevalence of single‐unit plasma transfusion in adults within a 12‐hospital system from 1 January 2018, to 31 December 2019.ResultsDuring the study period, 5791 patients received plasma transfusions. The overall prevalence of single‐unit plasma was 17.1% for 988 patients. The majority, 3047 (52.6%), occurred at one hospital, 2132 (36.9%) among five hospitals and 612 (10.7%) at the remaining six hospitals. Cardiac and gastrointestinal (GI)/transplant transfused 2707 (46.8%), combined respiratory, neurological, orthopaedic and congenital/dermatology/other comprised 2133 (36.9%) of the six hospitals that transfused less than 200 patients, four (66.7%) transfused single units above the overall prevalence.ConclusionIn this hospital system, more than one in six patients received a transfusion of a single plasma unit. Six of the 12 hospitals had 89.5% of the patients who were transfused plasma. Six service lines transfused 83.7% of all patients receiving plasma. Hospitals that infrequently transfused plasma were more likely to under‐dose.

show abstract

Noninfectious transfusion-associated adverse events

Cited by 2 publications

References 0 publications

Understanding the Immunological Significance of Blood Groups in Organ Transplantation

Understanding the Immunological Significance of Blood Groups in Organ Transplantation

Is it time for the death knell of single‐unit plasma?

Contact Info

Product

Resources

About